Antidepressant Effect of Theta-Burst rTMS

Status Recruiting

Clinical Trial Summary

The aim of this study is to evaluate the safety and efficacy of theta-burst rTMS in patients with major depression. Patients will be randomized to receive ether left-sided intermittent theta-burst rTMS or rigt-sided continuous theta-burst rTMS or sham theta-burst rTMS over two weeks period with an option for an additional two weeks period, depending on treatment response. Clinical assessments will be performed weekly by the Hamilton depression rating scale. In addition, standard neurophysiological assessment of cortical excitability will be done.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00515658
Study type	Interventional
Source	Rambam Health Care Campus
Contact	Ehud Klein, MD
Phone	972-4-8543599
Email	e_klein@rambam.health.gov.il
Status	Recruiting
Phase	Phase 2
Start date	March 2007

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