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Major Depression clinical trials

View clinical trials related to Major Depression.

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NCT ID: NCT01178255 Terminated - Major Depression Clinical Trials

Efficacy and Safety of Homeopathy for Moderate Depression (Acute Phase)

DEP-HOM
Start date: August 2010
Phase: Phase 3
Study type: Interventional

To assess the two components of individualized homeopathic treatment for acute depression, i.e., to investigate the specific effect of individualized Q-potencies versus placebo and to investigate the effect of different approaches to the homeopathic case history taking(defined in this study as case history taking type I and II).

NCT ID: NCT01135758 Terminated - Major Depression Clinical Trials

Study of Depression-Ketamine-Brain Function

Start date: June 2010
Phase: Phase 2
Study type: Interventional

Targeting the glutamatergic system to treat depression is a new and promising strategy based on studies at the molecular, synaptic, and neuronal level but also on results of studies conducted in animal models and first clinical studies involving depressed patients.Ketamine has been proposed as a novel approach to induce rapid antidepressant response. In this pilot project the investigators aim to introduce this novel and promising approach into clinical practice. Besides the assessment of clinical efficacy, the investigators will put a special emphasis on the assessment of ketamine-associated effects on brain function using fMRI and cognitive testing.

NCT ID: NCT01124344 Terminated - Major Depression Clinical Trials

Safety and Pharmacology Study of BMS-866949

Start date: May 2010
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to determine whether multiple doses.of BMS-886949 are safe and tolerable

NCT ID: NCT01119430 Terminated - Major Depression Clinical Trials

Fluoxetine Versus Fluoxetine Plus DU125530 in Major Depressive Disorder

Start date: May 2004
Phase: Phase 2
Study type: Interventional

The purpose of this study is to examine whether the speed of the clinical antidepressant action of fluoxetine can be accelerated by administering DU125530 a full 5-HT1A antagonist.

NCT ID: NCT00700609 Terminated - Depressive Disorder Clinical Trials

Family Based Treatment of Depressed Adolescents

BudFam
Start date: June 2008
Phase: Phase 2
Study type: Interventional

The purpose of this project is to assess the effectiveness of a family-based therapy (Attachment based family therapy-ABFT) for Norwegian adolescents (13-17 years) referred to specialist mental heath clinics.

NCT ID: NCT00695552 Terminated - Major Depression Clinical Trials

The Effect of Exercise on Depressive Symptoms in Unmedicated Patients

DEMOII
Start date: September 2008
Phase: N/A
Study type: Interventional

This trial investigates the biological effect of exercise training on depression. Participants will randomly be allocated to either a aerobic exercise group performing exercise on stationary bikes or a group performing low-impact exercise such as stretching exercises. Both groups will attend sessions three times per week for 3 months. Before and after the intervention the investigators will measure the severity of depression using the Hamilton depression rating scale (HAM-D17).

NCT ID: NCT00660062 Terminated - Major Depression Clinical Trials

Relapse Prevention With Escitalopram or Nortriptyline Following Electro-Convulsive Treatment (DUAG-7)

DUAG-7
Start date: August 2009
Phase: Phase 4
Study type: Interventional

The main purpose of this study is to investigate the relapse preventing efficacy of escitalopram in a dose range and nortriptylin in a single dose in patients having been treated successfully with a course of electroconvulsive treatment (ECT).

NCT ID: NCT00325000 Terminated - Major Depression Clinical Trials

Interpersonal Psychotherapy for Severely Depressed Inpatients

Start date: November 2000
Phase: N/A
Study type: Interventional

We examined the hypotheses that severely depressed inpatients treated for 5 weeks with IPT-S plus pharmacotherapy have 1) a higher reduction in depressive symptoms and 2) higher response- and remission rates compared to pharmacotherapy plus CM. For the follow-up period (12 months) we hypothesized a better symptomatic and psychosocial longterm outcome and lower rates of relapse for patients initially treated with combination therapy.

NCT ID: NCT00296686 Terminated - Major Depression Clinical Trials

Sequential Tranylcypromine (TC), TC + Dextroamphetamine and TC + Triiodothyronine for Refractory Depression

Start date: September 2001
Phase: Phase 4
Study type: Interventional

This pilot study will assess the efficacy of several sequential pharmacological treatments for patients with Refractory Depression.

NCT ID: NCT00203723 Terminated - Major Depression Clinical Trials

Use of Risperidone in ECT for Treatment Resistant Depression

Start date: March 2005
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine if the combination of risperidone and ECT improves a patient's response in depression compared to ECT alone.