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Macular Edema clinical trials

View clinical trials related to Macular Edema.

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NCT ID: NCT05698329 Recruiting - Clinical trials for Diabetic Macular Edema

Effect of AIV007 by Periocular Administration in Subjects With nAMD or DME

Start date: March 2, 2023
Phase: Phase 1
Study type: Interventional

To determine safety, pharmacokinetics, and duration of effect of periocularly administered AIV007 gel suspension in subjects with neovascular age-related macular degeneration (nAMD) or diabetic macular edema (DME).

NCT ID: NCT05642325 Recruiting - Clinical trials for Uveitic Macular Edema

Vamikibart in Participants With Uveitic Macular Edema

Sandcat
Start date: March 23, 2023
Phase: Phase 3
Study type: Interventional

This study will assess the efficacy and safety of vamikibart in participants with uveitic macular edema.

NCT ID: NCT05642312 Recruiting - Clinical trials for Uveitic Macular Edema

A Study to Investigate Vamikibart in Participants With Uveitic Macular Edema

Meerkat
Start date: January 9, 2023
Phase: Phase 3
Study type: Interventional

This study will assess the efficacy and safety of vamikibart in participants with uveitic macular edema.

NCT ID: NCT05626478 Recruiting - Corneal Edema Clinical Trials

Assessing eFficacy and Safety of DEXTENZA 0.4 mg inseRt, Following Cataract Surgery

Start date: June 1, 2023
Phase: Phase 4
Study type: Interventional

Assessing eFficacy and Safety of DEXTENZA 0.4 mg inseRt, Following Cataract Surgery

NCT ID: NCT05610319 Recruiting - Clinical trials for Diabetic Macular Edema

Treat & Extend Versus Fixed Dosing With Faricimab for Management of Diabetic Macular Edema: A Pragmatic, Multi-center, Open-label, Randomized, Controlled Trial

INSITE-DME
Start date: May 1, 2023
Phase: Phase 4
Study type: Interventional

This study will assess a pragmatic, treat and extend regimen of faricimab against the standard of a fixed dosing regimen.

NCT ID: NCT05608837 Recruiting - Clinical trials for Uveitis Related Cystoid Macular Edema

Multicenter Study on the Efficacy and Safety of OCS-01 in Subjects With Uveitis Related and Post Surgical Macular Edema

LEOPARD
Start date: May 26, 2023
Phase: Phase 2
Study type: Interventional

The goal of the LEOPARD clinical trial is to investigate a new kind of steroid eye drops, OCS-01. Macular edema is a condition in which there is collection of fluid (edema) in the back of the eye (Macula) and it can lead to severe loss of vision. Among other causes, macular edema can happen because of a disease of the eye called Uveitis, and also after eye surgery. Treatment of macular edema remains a challenge as the condition may persist for several months and may lead to irreversible changes in the eye and poor vision. In the LEOPARD study the investigators wish to see how safe is the study drug (OCS-01) and how well it works, in resolving the fluid collection in the eye in patients with Uveitis or in patients who have had eye surgery. Participants will undergo detailed eye exam, and record their eye and medical history to see what their disease status is and if they can be included in the study based on the study criteria. If included, they will take the study drug OCS-01 in different doses for 24 weeks. During the study period, they will have regular eye exams to ensure their safety and to assess the usefulness of the study drug.

NCT ID: NCT05529589 Recruiting - Vitreous Hemorrhage Clinical Trials

Comparison of Restoration in Vitreous Hemorrhage Patients With DME After or Not Removing Inner Limiting Membrane

Start date: February 10, 2023
Phase:
Study type: Observational

This study is conducted to compare the anti-VEGF effect and visual function in vitreous hemorrhage patients with diabetic macular edema after pars plana vitrectomy with inner limiting membrane peeling or not

NCT ID: NCT05496530 Recruiting - Clinical trials for Diabetic Macular Edema

Custom Needle Preparation for Suprachoroidal Steroid Injection (One Year Results)

Start date: July 10, 2022
Phase: N/A
Study type: Interventional

Suprachoroidal drug delivery is a recent route for managing various ocular conditions. Safety and long term results are still under investigations.

NCT ID: NCT05494775 Recruiting - Clinical trials for Diabetic Retinopathy

Effect of Corona Virus on Intravitreal Injections

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

During pandemic of corona virus, patients compliance may be affected. We aim to study the factors lead to unregulated visits and its implications on the final visual outcome.

NCT ID: NCT05476926 Recruiting - Clinical trials for Diabetic Macular Edema

A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology Products

VOYAGER
Start date: November 21, 2022
Phase:
Study type: Observational

The VOYAGER study is a primary data collection, non-interventional, prospective, multinational, multicenter study. It is designed to collect real-world, long-term data to explore long-term effectiveness, safety, clinical insights, treatment patterns, and factors driving the treatment decisions among patients being treated with specified Roche ophthalmology products (Faricimab and Port Delivery System with Ranibizumab) in approved retinal indications (neovascular age-related macular degeneration [nAMD] and diabetic macular edema [DME]) in routine clinical practice. This study will not provide or make recommendations on use of any products including Roche products; treatment decisions will be determined by the treating physician and must be made independently to the decision to participate in this study. Participation in this study will not change or influence a patient's standard of care in any way.