Lymphedema Clinical Trial
Official title:
The Efficacy and Safety of Immediate Axillary Plasty With Pedicled Partial Latissimus Dorsi Muscle Flap for Lymphedema Prevention in Breast Cancer Patients Who Undergoing Axillary Dissection: a Prospective, Corhort Study
The purpose of this comparable cohort study is to evaluate the efficacy and safety of immediate axillary plasty with pedicled partial Latissimus Dorsi muscle flap for lymphedema prevention in breast cancer patients who are undergoing axillary dissection.
Upper limb lymphedema is the main complication of axillary dissection. It is estimated that
as many as 50% of patients undergoing lymph node dissection go on to develop lymphedema,
with significantly decreased quality of life with frequent infections, decreased range of
motion, and a cosmetic deformity. The treatment of lymphedema was be frustrated by technical
difficulties and gave rise to a heavy budget burden. Some retrospective studies revealed
that immediate and delayed breast reconstruction with lattismus dorsi flap brought
unexpected relief to the upper limb lymphedema. The current study was composed to assess
whether transferring a pedicled partial latissimus dorsi muscle flap to the axilla would
prevent the occurrence of post-mastectomy lymphedema.
This prospectively designed cohort study have two parallel arms. Patients undergoing
axillary dissection would be recruited to one of the two groups, according their own
preference.
;
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Prevention
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