Lymph Node Metastases Clinical Trial
Official title:
Lymph Node Mapping Via the Flourescent Dye ICG in Colon Cancer Through Preoperative Application
The aim of the study is to evaluate whether lymph nodes draining the region of the carcinoma are located only inside the lines of standard resection or in some percentages are located outside as well. The visualized nodes draining the region of the carcinoma will be correlated to location, fluorescent yes/no and nodal positive/negative. The draining lymph nodes will be visualized using the fluorescent dye indocyanine green. The aim of the study is to evaluate whether lymph nodes draining the region of the carcinoma are located only inside the lines of standard resection or in some percentages are located outside as well. The visualized nodes draining the region of the carcinoma will be correlated to location, fluorescent yes/no and nodal positive/negative. The draining lymph nodes will be visualized using the fluorescent dye indocyanine green.
Participants with a diagnosed (andeno)carcinoma of the ascending, transverse, descending and sigmoid colon will be included. Preoperatively the participants will receive an indocyanine green(ICG) injection at four points around the tumour endoscopically. The ICG marking will take place one to five days prior to surgery. In the draining lymph nodes of the specific region the ICG will accumulate and thus visible via fluorescence-camera during the surgery. Intraoperatively, the precise locations of all fluorescent nodes will be documented photographically. A standard resection and lymph node dissection will be conducted, potential fluorescent nodes outside the standard resection lines will additionally be resected. The fresh specimen will then be measured, the fluorescent nodes marked and after the pathologic examination the nodes will be correlated to location, fluorescent yes/no and nodal positive/negative. The aim ist not the visualization of the Sentinel node or the directly draining lymphatic vessel but all the nodes draining the peritumorous region at the point of surgery. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03280719 -
Whole Breast + Lymph Node Irradiation: Prone Compared to Supine Position in 15 or 5 Fractions
|
N/A | |
Active, not recruiting |
NCT04300673 -
Radio Guided Lymph Node Dissection in Oligometastatic Prostate Cancer Patients
|
Phase 1/Phase 2 | |
Completed |
NCT04260139 -
Lymph Node Yield in Colon Cancer Resection Specimens
|
||
Not yet recruiting |
NCT03632746 -
Verifying the Specificity of a New Method in Predicting Lymph Node Metastasis in Early Gastric Cancer Patients
|
||
Active, not recruiting |
NCT03776591 -
Open D3 Right Hemicolectomy Compared to Laparoscopic CME for Right Sided Colon Cancer
|
N/A | |
Recruiting |
NCT05078853 -
Thyroglobulin Point of Care Assay for Rapid Detection of Metastatic Differentiated Thyroid Carcinoma
|
||
Recruiting |
NCT03715686 -
To Accurately Assess Lymph Node Response to NACT by Wire Localization of Clip-marked Lymph Nodes
|
N/A | |
Recruiting |
NCT03280134 -
A Prospective Validation Cohort Study of a Prediction System on nSLN Metastasis in Early Breast Cancer
|
N/A | |
Recruiting |
NCT04117139 -
The Diagnostic Value of PET/MRI in Head and Neck Cancer
|
N/A | |
Recruiting |
NCT04882618 -
Use of Indocyanine Green During Pelvic Lymph Node Dissection in Prostate Cancer.
|
Phase 4 | |
Recruiting |
NCT05670574 -
Surgery With Extended (D3) Mesenterectomy for Small Bowel Tumors
|
N/A | |
Active, not recruiting |
NCT04611997 -
IGG Using in Laparoscopic Gastrectomy for Locally Advanced Gastric Cancer After Neoadjuvant Chemotherapy
|
Phase 3 | |
Recruiting |
NCT04744506 -
Targeted Resection of Axillary Metastatic Lymph Nodes After Breast Cancer Neoadjuvant Chemotherapy
|
N/A | |
Recruiting |
NCT03830242 -
Diagnostic Significance of FDG PET/CT Dynamic Imaging in Detecting Metastatic Lymph Nodes With Papillary Thyroid Cancer.
|
N/A | |
Active, not recruiting |
NCT04419935 -
Lymphadenectomy in NSCLC With and Without Adjuvant Therapy
|
||
Enrolling by invitation |
NCT04322331 -
Tumor Immune Mechanism of Axillary Lymph Node Metastasis in Early Luminal Type A Breast Cancer
|
||
Recruiting |
NCT03868215 -
Use of Plasma ctDNA Methylation Haplotypes in Detecting Local Residual or Lymph Node Metastasis
|
||
Recruiting |
NCT04337333 -
Two-in-one Covered and Uncovered Metal Stent
|
N/A | |
Completed |
NCT04068636 -
Sentinel Node in Larynx and Pharynx Cancers
|
N/A | |
Recruiting |
NCT04671511 -
Targeted Axillary Dissection (TAD) in Early-stage Node Positive Breast Cancer
|
N/A |