Lung Neoplasm Clinical Trial
Official title:
A Study to See if a New Type of Imaging Can Help Our Understanding of the Course of Non-small Cell Lung Cancer in Patients Undergoing Treatment With Radiotherapy or Chemoradiotherapy
Non-small cell lung cancer (NSCLC) has a poor prognosis if not caught early enough. One of the factors that may impact the ability to control NSCLC is low oxygen levels (hypoxia) inside the tumour. This study will use 18F-FAZA PET scans to assess whether patients have hypoxic tumours and to monitor the changes to the hypoxic areas of a tumour during currently available standard treatment. It is hypothesized that 18F-FAZA PET may predict response to treatment, local control, and/or survival in NSCLC.
Locally advanced NSCLC has a poor prognosis with a 5 year overall survival rate of only 15%. Tumour hypoxia may impact the ability to control NSCLC. Using 18F-FAZA PET, this study will assess patients for hypoxic treatment. With this information, we can start individualizing patient treatment to target hypoxia. The relationship between areas of hypoxia (18F-FAZA) and high glucose utilization (18F-FDG) will also be assessed. ;
Observational Model: Cohort, Time Perspective: Prospective
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05078918 -
Comprehensive Care Program for Their Return to Normal Life Among Lung Cancer Survivors
|
N/A | |
| Completed |
NCT04508270 -
Significance of Early Mobilization After VATS-L
|
||
| Active, not recruiting |
NCT03667716 -
COM701 (an Inhibitor of PVRIG) in Subjects With Advanced Solid Tumors.
|
Phase 1 | |
| Completed |
NCT05469425 -
Home-based Preoperative Exercise Training for Lung Cancer Patients Undergoing Surgery
|
N/A | |
| Recruiting |
NCT05046067 -
Feasibility Study of Anatomical Modeling for Image Guided Thoracic Surgery
|
N/A | |
| Terminated |
NCT03090880 -
Prophylaxis of Venous Thromboembolism in Advanced Lung Cancer (PROVE)
|
Phase 3 | |
| Recruiting |
NCT05596760 -
Promoting Goals-of-Care Discussions for Patients With Memory Problems and Their Caregivers
|
N/A | |
| Completed |
NCT02498860 -
Efficacy and Safety of Adjuvant Pemetrexed Plus Cisplatin for Adenocarcinoma of Lung
|
Phase 2 | |
| Completed |
NCT02952261 -
Application of 3D Printing Technique in Small Pulmonary Nodule Localization
|
N/A | |
| Not yet recruiting |
NCT06024538 -
Role of Cancer-associated Fibroblast, MDSCs and Immune Cell Interplays in the Resistance of Non-small Cell Lung Cancer to Anti-PD1/PD-L1 Therapies
|
||
| Recruiting |
NCT02965300 -
The Value of VOCs Analysis in Exhaled Breath for Pulmonary Benign and Malignant Lesion Diagnosis
|
N/A | |
| Completed |
NCT02616211 -
An Integrated Approach to Treating Recurrent Thoracic Carcinomas Resistant to Tyrosine Kinase Inhibitors
|
||
| Completed |
NCT03320044 -
Early Diagnosis of Small Pulmonary Nodules by Multi-omics Sequencing
|
||
| Recruiting |
NCT03655015 -
Patient-derived Organoid Model and Circulating Tumor Cells for Treatment Response of Lung Cancer
|
||
| Completed |
NCT03741868 -
Symptom Burden and Unmet Supportive Care Needs in Lung Cancer Patients Undergoing First or Second Line Immunotherapy
|
||
| Not yet recruiting |
NCT05179408 -
Telerehabilitation Following Lung Cancer
|
N/A | |
| Completed |
NCT03749512 -
NLCR in Prediction of the Grade of Lung Tumor.
|
||
| Recruiting |
NCT03664843 -
Circulating Tumor DNA Longitudinal Monitoring in Stage III-IV Lung Cancer Patients
|
||
| Completed |
NCT01261507 -
Reader Study of DeltaView™ Chest Radiograph Software
|
N/A | |
| Terminated |
NCT01064050 -
Role of a Silicone Prosthesis to Prevent Airway Obstruction Recurrence in Lung Cancers
|
Phase 4 |