Lung Diseases Clinical Trial
Official title:
Bronchoalveolar Lavages in the Intensive Care Unit : Indications, Adverse Respiratory Effects, Contribution to Diagnosis and Therapy. A Multicenter, Prospective, Observational Study
Little is known about bronchoalveolar lavages performed for cytological assessment during
bronchial fibroscopy in critically ill patients. Frequency of use, indications, actual
contribution to diagnosis and therapeutic decision, and complications have not been
extensively assessed.
The primary objective of this multi center, prospective, observational study is to describe
the frequency of use of bronchoalveolar lavages for cytological assessement in critically ill
patients, identify their indications, assess their contribution to diagnosis and therapeutic
decisions, and estimate the frequency of induced respiratory events.
Secondary objectives will be to
- assess the frequency of poor quality bronchoalveolar lavages (as defined by either more
than 5% bronchial epithelial cell count to less than 50,000 alveolar cells per mL)
- assess the contribution of a given bronchoalveolar lavage to the diagnostic work up
- assess the contribution of a given bronchoalveolar lavage results to therapeutic
decision
- assess the induced short term respiratory side effects
- identify risk factors for poor respiratory tolerance
;
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