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Lung Diseases, Obstructive clinical trials

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NCT ID: NCT05814484 Not yet recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Role of Inhaler Adherence and Blood Eosinophil Count in Exacerbations of COPD

INCLINE
Start date: August 10, 2023
Phase:
Study type: Observational

This is an observational study examining inhaler adherence and subsequent changes in blood eosinophil count in exacerbations of Chronic obstructive pulmonary disease (COPD) population. The study will run for 6 months as an observation period. Passive inhaler adherence monitoring will be done electronically via inhaler sensors connected to mobile Apps, and collecting symptoms questionnaires, diary of exacerbation events and trial visits predominantly in remote fashion. It will explore the feasibility of digital platform in clinical practice to collect the adherence data along with exacerbation events.

NCT ID: NCT05813652 Recruiting - Diabetes Mellitus Clinical Trials

Relative Impacts on Preventative Primary Care--a Longitudinal Evaluation of COVID-19:Phase 1

RIPPLE-C
Start date: October 5, 2022
Phase:
Study type: Observational

The goal of this observational study is to describe the impacts of COVID-19 on primary care chronic condition management in Canada within various patient populations. This will be done by analyzing primary care electronic medial record (EMR) data from the Canadian Primary Care Sentinel Surveillance Network (CPCSSN) database, including data on primary care encounters, as well as various markers for chronic conditions. The research questions to be investigated are: 1a) What are the changes to the management of chronic conditions in primary care since the onset of the COVID-19 pandemic? 1b) How do these changes differ by age, health status, and socioeconomic status?

NCT ID: NCT05811832 Recruiting - Clinical trials for COPD (Chronic Obstructive Pulmonary Disease)

Evaluation in Elderly Individuals With Chronic Obstructive Pulmonary Disease(COPD)

Start date: December 15, 2022
Phase:
Study type: Observational [Patient Registry]

This study is conducted on the evaluation of balance, physical activity, functional capacity and activities of daily living in frail elderly individuals with COPD.

NCT ID: NCT05808621 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Muscle Oxygenation in Chronic Obstructive Pulmonary Disease

Start date: March 8, 2023
Phase:
Study type: Observational

The aim of our study is to examine the Peripheral Muscle Oxygenations at rest and in motion on the 2nd day of hospitalized patients and before discharge in Severe Acute Exacerbation of Chronic Obstructive Pulmonary Disease and to compare the results in the hospital periods by repeating the tests in the stable periods of the patients 1 month after discharge.

NCT ID: NCT05806294 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Digital Metabolic Rehabilitation COPD

Start date: November 17, 2022
Phase: N/A
Study type: Interventional

People with Chronic Obstructive Pulmonary Disease (COPD) are at greater risk for Metabolic syndrome (MetS). Although the management of MetS will not cure COPD, it can beneficially impact health outcomes and quality of life through lifestyle modifications. The study aims to determine if using the Digital Metabolic Rehab program, which is based on preventive self-care and includes three key pillars of health: nutrition, fitness, and mindfulness, will be feasible to reduce or reverse MetS for individuals living with COPD.

NCT ID: NCT05805332 Not yet recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Evaluation of Skeletal Muscle Function Using Ultrasonic Elastography

Start date: April 7, 2023
Phase:
Study type: Observational

The goal of observational study is to evaluation of skeletal muscle function in patients with chronic obstructive pulmonary disease before and after lung rehabilitation training using ultrasonic elastography in Chronic Obstructive Pulmonary Disease. The main question it aims to answer are:Evaluation of skeletal muscle function in patients with chronic obstructive pulmonary disease before and after lung rehabilitation training using ultrasonic elastography. Participants will undergo pulmonary rehabilitation.

NCT ID: NCT05799040 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Evaluation of the Effectiveness of the Self-developed Pulmonary Lobar Ventilation Detector

Start date: October 26, 2023
Phase:
Study type: Observational

The goal of observational study is to Evaluation of the effectiveness of the self-developed pulmonary lobar ventilation detector in Chronic Obstructive Pulmonary Disease. The main question it aims to answer are:Evaluation of the effectiveness of the self-developed pulmonary lobar ventilation detector. Participants will use the self-developed pulmonary lobar ventilation detector and the imported Chartis detection system to evaluate the target pulmonary lobar collateral ventilation.

NCT ID: NCT05793697 Not yet recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Assessment Of Different Scores In Predicting Outcome In AECOPD Patients In Emergency Department

Start date: May 3, 2023
Phase:
Study type: Observational [Patient Registry]

evaluate the value of different scores in predicting hospital mortality and Need for MV In patients presented to ED with AECOPD.

NCT ID: NCT05786950 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Neural Respiratory Drive of Patients With Chronic Obstructive Pulmonary Disease

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

To investigate the relationship among the neural respiratory drive (NRD), the sensation of the dyspnea and the effect of the bronchodilator on each stage COPD patients.

NCT ID: NCT05785195 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

A Mechanistic Study of Inhaled Nitric Oxide in COPD

Start date: March 14, 2023
Phase: N/A
Study type: Interventional

There is a lack of effective treatments for chronic obstructive pulmonary disease (COPD) complicated with pulmonary hypertension. Previous studies have found that inhaled nitric oxide (iNO) can reduce pulmonary artery pressure and improve exercise capacity in COPD with pulmonary hypertension patients. However, the specific mechanism is unclear. The study aims to evaluate pulmonary ventilation/perfusion, pulmonary artery pressure, oxygenation, symptoms and quality of life in COPD with pulmonary hypertension patients after short-term treatment with iNO. Observing a series of pathophysiological changes caused by the treatment of pulmonary hypertension with iNO in COPD, the investigators hope to provide new theoretical basis and research ideas.