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Lung Cancer clinical trials

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NCT ID: NCT04236102 Completed - Lung Cancer Clinical Trials

KEBI-Cyto Study - Use of the Biocartis Idylla

Start date: July 7, 2020
Phase: N/A
Study type: Interventional

Use of the Biocartis Idylla ™ platform for the detection of Epidermal Growth Factor Receptor, B-RAF and K-RAS proto-oncogene mutations in liquid based cytology specimens and blood plasma samples from patients with non small cell lung carcinoma and pancreatic adenocarcinoma.

NCT ID: NCT04233476 Completed - Lung Cancer Clinical Trials

99mTc-3PRGD2 SPECT/CT for Integrin Imaging of Lung Cancer

TRIIL
Start date: October 12, 2019
Phase: Phase 3
Study type: Interventional

This is a prospective, multicenter, self-controlled phase 3 clinical trial designed to evaluate the safety and efficacy of an integrin αVβ3-targeted imaging, 99mTc-3PRGD2 SPECT/CT, for diagnosis of lung cancer and mapping the lymph node metastases. The pathological results will be considered as the gold standard and the conventional metabolic imaging by 18F-FDG PET/CT will be used for a head-to-head comparison. The primary objective of this study is to evaluate the efficacy of 99mTc-3PRGD2 SPECT/CT in mapping of lymph node metastasis according to the nodal mapping system released by the International Association for the Study of Lung Cancer in 2009 (IASLC-2009). The secondary objectives include evaluation of 99mTc-3PRGD2 SPECT/CT in detection of lung cancer and the safety of 99mTc-3PRGD2 injection in human beings.

NCT ID: NCT04227457 Completed - Lung Cancer Clinical Trials

Prospective Epidemiological Study of Metastatic Non Small Cell Lung Cancer (NSCLC) in Latin America

LATINO Lung
Start date: July 25, 2018
Phase:
Study type: Observational [Patient Registry]

To describe the overall survival of advanced NSCLC in Latin America.

NCT ID: NCT04217655 Completed - Lung Cancer Clinical Trials

Low-dose Computed Tomography-guided Core Needle Biopsy for Lung Nodules

Start date: June 1, 2020
Phase: N/A
Study type: Interventional

Investigators aim to compare the diagnostic accuracy and radiation exposure between low-dose and standard-dose computed tomography-guided core needle biopsy for lung nodules.

NCT ID: NCT04182815 Completed - Lung Cancer Clinical Trials

Transbronchial Biopsy Assisted by Robot Guidance in the Evaluation of Tumors of the Lung

TARGET
Start date: December 10, 2019
Phase:
Study type: Observational

This study is designed to evaluate clinical safety and diagnostic accuracy of the robotic-assisted bronchoscopy with biopsy performed with the Monarch™ Endoscopy Platform in a broad range of patients with pulmonary lesions.

NCT ID: NCT04172506 Completed - Lung Cancer Clinical Trials

A Study to Evaluate the Efficacy and Safety of Anti-PD-1 Antibody AK105 in Patients With Selected Advanced Solid Tumors

Start date: September 10, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

This is a multi-center, multi-cohort, open-label, phase Ib/II study to evaluate the efficacy, safety, PK characteristics, immunogenicity and potential biomarkers of AK105 monotherapy in the patients with selected advanced solid tumors.

NCT ID: NCT04145570 Completed - Lung Cancer Clinical Trials

A Single-Dose,ComparativeBioavailability Study ofTwo Formulations ofErlotinib150mgTabletsunderFastingConditions

Start date: October 23, 2008
Phase: Phase 4
Study type: Interventional

Theobjectiveofthisstudyistoevaluatethecomparativebioavailabilitybetween: - ErlotinibHCl150mgTablets(Novopharm Limited,Canada)and - Tarceva® 150mgTablets(Hoffmann-LaRocheLimited,Canada) afterasingle-doseinhealthysubjectsunderfastingconditions.

NCT ID: NCT04139408 Completed - Lung Cancer Clinical Trials

Safety and Effectiveness of Disposable Pulmonary Surgical Markers in the Localization of Pulmonary Nodules

Start date: July 22, 2020
Phase: N/A
Study type: Interventional

During the VATS procedure, some pulmonary nodules are relatively small or far away from the pleura, resulting that they are difficult to be accurately located during the procedure. The aim of this study is to evaluate the efficacy and safety of using disposable pulmonary surgical markers to localize pulmonary nodules in subjects prior to the resection of pulmonary nodules by video-assisted thoracoscopic surgery (VATS).

NCT ID: NCT04131426 Completed - Lung Cancer Clinical Trials

Evaluating the Combined Intervention of Nutritional Supplementation (Remune) and Exercise in Patients With Cancer Cachexia

Start date: April 24, 2020
Phase: Phase 1
Study type: Interventional

The main purpose of this research study is to determine if the use of a nutritional supplement and exercise improve or worsen cachexia.

NCT ID: NCT04119960 Completed - Lung Cancer Clinical Trials

Clinical Validation of InferRead Lung CT.AI

Start date: January 10, 2019
Phase:
Study type: Observational

Lung cancer is the second most common cause of cancer-related death in men and women. Early pulmonary nodule screening is an effective means to prevent lung cancer, which is no less important than the diagnosis and treatment of lung cancer. Early lung cancer screening has been investigated and applied as a medical practice. InferRead Lung CT.AI by Infervision is a dedicated post processing application that generates CADe marks as an overlay on the original CT series intended to aid the radiologist in the detection of pulmonary nodules. This study was designed to evaluate radiologists' performance in detecting actionable nodules on chest CT when aided by InferRead.