Lumbar Spondylolisthesis Clinical Trial
Official title:
Incidence of Lumbar Spondylolisthesis in Patients Candidate for Total Knee Replacement
This study aims to detect the incidence of spondylolisthesis in patients candidate for Total knee replacement (TKR) and to investigate the effect of TKR on the course of low back pain.
Status | Not yet recruiting |
Enrollment | 60 |
Est. completion date | June 2024 |
Est. primary completion date | May 2024 |
Accepts healthy volunteers | |
Gender | All |
Age group | 40 Years and older |
Eligibility | Inclusion Criteria: - primary end-stage knee osteoarthritis. Exclusion Criteria: - secondary inflammatory knee osteoarthritis. - post traumatic knee osteoarthritis. - patients with active infection. - patients with poor general condition. - patients who had previous spinal fixation or fusion surgery. |
Country | Name | City | State |
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n/a |
Lead Sponsor | Collaborator |
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Assiut University |
Chang CB, Park KW, Kang YG, Kim TK. Coexisting lumbar spondylosis in patients undergoing TKA: how common and how serious? Clin Orthop Relat Res. 2014 Feb;472(2):710-7. doi: 10.1007/s11999-013-3298-7. Epub 2013 Sep 25. — View Citation
Kahlenberg CA, Nwachukwu BU, McLawhorn AS, Cross MB, Cornell CN, Padgett DE. Patient Satisfaction After Total Knee Replacement: A Systematic Review. HSS J. 2018 Jul;14(2):192-201. doi: 10.1007/s11420-018-9614-8. Epub 2018 Jun 5. — View Citation
Londhe SB, Shah RV, Patwardhan M, Doshi AP, Londhe SS, Subhedar K, Kundnani V, Patel J. Study of Patients with Bilateral Knee Osteoarthritis Undergoing Total Knee Replacement Procedure with Coexisting Lumbar Spondylosis Symptoms. Asian Spine J. 2021 Dec;15(6):825-830. doi: 10.31616/asj.2020.0279. Epub 2020 Dec 28. — View Citation
Patel EA, Perloff MD. Radicular Pain Syndromes: Cervical, Lumbar, and Spinal Stenosis. Semin Neurol. 2018 Dec;38(6):634-639. doi: 10.1055/s-0038-1673680. Epub 2018 Dec 6. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Incidence of lumbar spine spondylolisthesis. | showing the incidence and occurrence of Lumbar Spondylolisthesis in patients with severe knee Osteoarthritis which needs Total knee replacement | Baseline | |
Primary | Severity of lumbar spine spondylolisthesis. | showing the grades of lumbar spine spondylolisthesis through The Meyerding classification system with grade 1 is the minimum and grade 5 is the maximum which in turn has the worst outcome | Baseline | |
Primary | occurence of lumbar spine spondylolishtesis Occurrence of lumbar spine spondylolisthesis | Showing the occurrence of lumbar spine spondylolisthesis in patients with severe osteoarthritis which needs total knee replacement | Baseline | |
Secondary | Change in characters of low back pain over the postoperative period. | Recording the changes of the backpain after Total knee replacement using Oswestry disability index scale which is 0 is the minimum value and 100 is the maximum value which in turn presents with the worst outcome | 6 months follow up | |
Secondary | Spine radiological features. | Recording the radiological features of Lumber spine through plain xrays of to evaluate the presence of Spondylolisthesis | Baseline | |
Secondary | Knee radiological and alignment features. | Recording the radiological features of knee through plain xrays of to measure the hip knee ankle angle | Baseline |
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