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Lumbar Spondylolisthesis clinical trials

View clinical trials related to Lumbar Spondylolisthesis.

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NCT ID: NCT06255366 Not yet recruiting - Clinical trials for Lumbar Spondylolisthesis

Analysis of the Clinical Efficacy of Intravenous Application of Hemostatic Drugs in Improving the Clarity of Vision Under Endoscope, Perioperative Bleeding Volume and Anti-inflammatory Effect of Spinal Endoscopic Lumbar Fusion

Start date: March 28, 2024
Phase: Phase 4
Study type: Interventional

To study the clinical efficacy of carosodiumsulfonate and desmopressin in improving the clarity of vision under endoscope, perioperative bleeding volume and anti-inflammatory effect in endoscopic lumbar fusion

NCT ID: NCT06154005 Recruiting - Clinical trials for Degenerative Disc Disease

OsteoAdapt SP Advanced Bone Graft Feasibility Study - Transforaminal Interbody Lumbar Fusion

OASIS
Start date: May 1, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this clinical study is to assess the safety and effectiveness of the OsteoAdapt SP as a replacement for the autograft standard of care bone graft within the interbody cage, as well as identify the OsteoAdapt SP dose to be investigated in a future pivotal study.

NCT ID: NCT05993195 Active, not recruiting - Clinical trials for Degenerative Spondylolisthesis

Re-operation Rates of Concorde Bullet Device Versus Conduit Titanium Interbody Graft for Lumbar Fusion

Start date: March 12, 2021
Phase:
Study type: Observational

The purpose of this early study is to compare the clinical results of the new Conduit Interbody device to the traditional Concorde Bullet Device. The primary objective is to explore the rates and reasons for re-operation between both constructs at 2 years.

NCT ID: NCT05959343 Completed - Clinical trials for Lumbar Spinal Stenosis

Enhanced Recovery After Surgery in Oblique Lumbar Interbody Fusion

Start date: July 12, 2023
Phase: N/A
Study type: Interventional

This study is a randomized controlled non-inferiority trial designed to evaluate the impact of implementing the 'Early Recovery After Surgery Clinical Pathway (ERAS CP)' on patient-reported pain levels at the time of discharge following Oblique Lumbar Interbody Fusion (OLIF) surgery

NCT ID: NCT05945550 Active, not recruiting - Clinical trials for Lumbar Spondylolisthesis

Comparison of Complication Rates Between Initial and Re-operative Anterior Lumbar Interbody Fusion Surgery: Is There a Difference?

Start date: December 28, 2020
Phase:
Study type: Observational

To identify the current mortality rate for initial ALIF procedures. Establish/prove mortality rates for this operation have dropped in the past decade.

NCT ID: NCT05871073 Completed - Clinical trials for Lumbar Spinal Stenosis

Dexamethasone as Adjuvant to Ropivacaine in Wound Infiltration for Postoperative Analgesia Following Spinal Surgery

Start date: January 1, 2023
Phase: Phase 4
Study type: Interventional

Introduction: Improving postoperative pain management after spinal surgery is a significant challenge for surgeons and anesthesiologists. Pain following spinal surgery, can lead to significant morbidity, limit early mobility, and increase the risk of chronic pain. This trial examines the analgesic effects of dexamethasone as an adjuvant to ropivacaine in wound infiltration after lumbar surgery. Methods: In this study, we randomly assigned sixty patients undergoing lumbar laminectomy and/or osteosynthesis into two groups of 30 patients each. The control group (R-group) received only Ropivacaine (150 mg of Ropivacaine 7.5% (20 ml) added to 2 ml of normal saline in the wound infiltration), while the intervention group (RD-group) received Ropivacaine with the addition of dexamethasone (150 mg of Ropivacaine 7.5% (20 ml) added to 8 mg of dexamethasone in the wound infiltration). Both groups were administered patient-controlled analgesia (PCA) with morphine for self-medication. Postoperatively, a blinded evaluator assessed pain at H0, recorded the assessment of surgical scar pain using the Visual Analog Scale (VAS) at 4, 6, 12, 24, and 48 hours, as well as the time to the first opioid request, cumulative morphine consumption, opioid-related side effects, and length of stay. All patients were scheduled for a 3-month follow-up call to monitor chronic pain progression.

NCT ID: NCT05691062 Not yet recruiting - Spine Fusion Clinical Trials

Titanium vs. PEEK Fusion Devices in 1 Level TLIF

TLIF
Start date: June 1, 2023
Phase: Phase 4
Study type: Interventional

The objective of this study is to evaluate and follow the clinical and radiographic outcomes of patients undergoing 1 level TLIF randomized to either a titanium or a PEEK spacer to 24 months after surgery.

NCT ID: NCT05638399 Recruiting - Osteopenia Clinical Trials

Denosumab vs Zoledronate After Lumbar Fusion

Start date: January 15, 2020
Phase: Phase 3
Study type: Interventional

The aim of the study was to compare denosumab and zoledronate efficacy in bone mass, bone turnover markers (BTMs), Visual Analogue Scale (VAS) for leg and back, EuroQol Five-Dimension (EQ-5D) scores, Quality of Life Questionnaire of the European Foundation for Osteoporosis-31 (QUALEFFO-31) scores, and Roland-Morris Disability Functioning Questionnaire (RMDQ) scores, secondary fracture, complications and adverse events after lumbar fusion.

NCT ID: NCT05527145 Recruiting - Clinical trials for Lumbar Spinal Stenosis

Spinal Stenosis and Listhesis Treated With Percutaneous Interspinous Spacer: a Non-surgical Trial

Start date: September 2024
Phase: N/A
Study type: Interventional

Symptomatic lumbar spinal stenosis is the most common indication for spinal surgery. However, more than one-third of the patients undergoing surgery for lumbar stenosis report dissatisfaction with the results. On the other hand, conservative treatment has shown positive results in some cases. This trial will compare the outcomes of surgical versus non-surgical treatment for lumbar stenosis.

NCT ID: NCT05480267 Not yet recruiting - Clinical trials for Lumbar Spondylolisthesis

A RCT of UBE vs. MIS-TLIF in Lumbar Spondylolisthesis

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

Unilateral biportal endoscopy (UBE) is a new spinal minimally invasive technique improved for the treatment of lumbar spondylolisthesis (LSP). The present study aims to establish a multicenter, large sample, randomized controlled study to explore the technical advantages and surgical indications of this new technique in the treatment of LSP by comparing with the classical minimally invasive posterior spinal interbody fusion; to compare the postoperative clinical and imaging results and analyze the surgical complications and preventive measures.