Lower Urinary Tract Symptoms Clinical Trial
— UroLUTSOfficial title:
Prospective Cohort Study of Patients With Lower Urinary Tract Dysfunction Undergoing Urodynamic Examination for the Assessment of Quality, Cost and Treatment Success
NCT number | NCT05809154 |
Other study ID # | UroLUTS |
Secondary ID | |
Status | Withdrawn |
Phase | |
First received | |
Last updated | |
Start date | January 2019 |
Est. completion date | January 2026 |
Verified date | March 2023 |
Source | University Hospital Inselspital, Berne |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational [Patient Registry] |
Lower urinary tract dysfunction (LUTD) is a very common complication of urological, gynecological, neurological, metabolic, inflammatory or tumor disease. LUTD is not an inevitable condition, the investigators can help in many ways. Modern clinical examinations like urodynamics allow for patient tailored treatment strategies. Urodynamics however, even if minimal invasive, may lead to urinary tract infections and are very expensive4. Aim of this study is to evaluate in the long-term perspective what patients profit of urodynamic examinations and in what patients the investigators could resign to perform urodynamics in the future and or in what patients the interval of urodynamics could be extended. Main objective is to follow in a long-term prospective cohort study, patients suffering of lower urinary tract dysfunction (LUTD). In this observational study the investigators will include all patient undergoing clinical routine urodynamic examination to better address what is the normal course of LUTD with and without Treatment. The aim is to have a prospective urodynamics database allowing to answer questions related to urodynamics.
Status | Withdrawn |
Enrollment | 0 |
Est. completion date | January 2026 |
Est. primary completion date | January 2025 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - Participants fulfilling all of the following inclusion criteria are eligible for the study: - Female and male patients, age >18 years - Informed consent - Lower urinary tract symptoms - Planned clinical routine urodynamic examination Exclusion Criteria: - The presence of any of the following exclusion criteria will lead to exclusion of the participant: - Age <18 years - Pregnancy or breast feeding - Individuals especially in need of protection (according to Research with Human Subjects published by the Swiss Academy of Medical Sciences https://www.samw.ch/en/Publications/Medical-ethical-Guidelines.html) - No informed consent - Patients incapable to follow the trial, e.g. because of language problems, psychiatric disorders, dementia and so on. |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
University Hospital Inselspital, Berne |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Number of voids per 24 hours | Number of voids per 24 hours | At the urodynamic assessment, up to 24 hours | |
Primary | Number of leakages per 24 hours | Number of leakages per 24 hours | At the urodynamic assessment, up to 24 hours | |
Primary | Number of used pads per 24 hours | Number of used pads per 24 hours | At the urodynamic assessment, up to 24 hours | |
Primary | Post void residual (mL) | Residual urine remaining in the bladder after voiding. | At the urodynamic assessment, up to 10-30 minutes | |
Secondary | Cystometric capacity (mL) | Measured in mL in urodynamics | At the urodynamic assessment, up to 10-30 minutes | |
Secondary | Compliance (mL/cmH2O) | Measured in mL/cmH2O in urodynamics | At the urodynamic assessment, up to 10-30 minutes | |
Secondary | Bladder volume (mL) at detrusor overactivity | Measured in mL in urodynamics | At the urodynamic assessment, up to 10-30 minutes | |
Secondary | Maximum detrusor pressure amplitude (cmH2O) at detrusor overactivity | Measured in cmH2O in urodynamics | At the urodynamic assessment, up to 10-30 minutes | |
Secondary | Detrusor leak point pressure (cmH2O) | Measured in cmH2O in urodynamics | At the urodynamic assessment, up to 10-30 minutes | |
Secondary | Maximum detrusor pressure (cmH2O) during storage phase | Measured in cmH2O in urodynamics | At the urodynamic assessment, up to 10-30 minutes | |
Secondary | Maximum detrusor pressure (cmH2O) during voiding phase | Measured in cmH2O in urodynamics | At the urodynamic assessment, up to 10-30 minutes | |
Secondary | Detrusor pressure at maximum flow | Measured in urodynamics | At the urodynamic assessment, up to 10-30 minutes | |
Secondary | Scores in Qualiveen & International Prostate Symptom Score (IPSS) | At the urodynamic assessment, up to 10-30 minutes | ||
Secondary | Scores in Female Sexual Function Index (FSFI) or International Index of Erectile Function (IIEF) | At the urodynamic assessment, up to 10-30 minutes | ||
Secondary | Number of patients with adverse events grade 1 bis 5 following the National Cancer Institute terminology Vers. 4 (Common Terminology Criteria for Adverse Events (CTCAE) | At the urodynamic assessment, up to 10-30 minutes |
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