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Lower Urinary Tract Symptoms clinical trials

View clinical trials related to Lower Urinary Tract Symptoms.

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NCT ID: NCT06466369 Active, not recruiting - Clinical trials for BPH With Other Lower Urinary Tract Symptoms

Administration of Tadalafil in Patients With Benign Prostatic Hyperplasia

Start date: March 15, 2024
Phase: Phase 3
Study type: Interventional

The aim of the present study is to evaluate the efficacy and safety of once daily administration PDE5 inhibitors, tadalafil for 3 months as anti-inflammatory, antiproliferative and relaxant effects in ED with BPH patients.

NCT ID: NCT06347614 Active, not recruiting - Prostate Cancer Clinical Trials

Modified Radical Prostatectomy for Prostate Cancer Patients With Enlarged Prostate and Severe Lower Urinary Tract Symptoms: a Single-center, Retrospective Study

Two-step RP
Start date: September 1, 2021
Phase:
Study type: Observational

The goal of this retrospective, observational study is to preliminarily learn about the safety and efficacy of two-step radical prostatectomy in the treatment of low- to intermediate-risk prostate cancer patients with enlarged prostate and severe benign prostatic hyperplasia. The main questions it aims to answer are: 1. Whether two-step prostatectomy is safe enough to decrease the surgical difficulty of these patients? 2. Whether the oncologic control is promising?

NCT ID: NCT06311110 Active, not recruiting - Clinical trials for Lower Urinary Tract Symptoms

Impaired Toilet Training, LUTS and Bowel Dysfunction in Children With DCD

Start date: October 30, 2023
Phase:
Study type: Observational

This cross-sectional case-control study aimed to determine whether there is a significant difference in the prevalence of impaired toilet training, LUTS, and functional bowel problems among children diagnosed with DCD and typically developing children (TDC).

NCT ID: NCT06290323 Active, not recruiting - Clinical trials for Lower Urinary Tract Symptoms

Effects of Quadratus Lumborum Block on Lower Urinary System Symptoms

Start date: January 25, 2024
Phase: N/A
Study type: Interventional

The most common reason for applying to a hospital in the postoperative period is due to the double J stent inserted during operations of the ureteroscopic lithotripsy, which is reflected pain (T11-L2). The posterior approximation QL block (QL-P) extends more quickly to the thoracic paravertebral cavity or thoracolumbar plane, creating analgesia from T 7' to L 1'. The effects of double J catheter in patients are followed by the 'Ureteral Stent Symptom Scoring Survey.' QL-P for postoperative analgesia after URS operations Our primary hypothesis in this prospective, randomized, controlled study is that the symptoms of the sub-urinary system associated with the DJS of the QL-P block will decrease. Our secondary hypotheses in the study are to investigate the effects of the unilateral QL-P block, made under ultrasound guidance, on pain scores after ureteroscopic lithotripsy operations due to unilateral ureteral stones made under spinal anesthesia.

NCT ID: NCT06051383 Active, not recruiting - Clinical trials for Benign Prostatic Hyperplasia

Outcome of Conducting Self-management Intervention on Severity of Lower Urinary Tract Symptoms

Start date: June 1, 2023
Phase: N/A
Study type: Interventional

Aim of this study is to evaluate the effect of conducting self-management interventions on severity of lower urinary tract symptoms (LUTS) for patients with benign prostatic hyperplasia (BPH). Research hypothesis: To fulfill the aim of this study, the following research hypothesis was formulated: Patients with benign prostatic hyperplasia will suffer less lower urinary tract symptoms (LUTS) after conducting self-management intervention than before conducting.

NCT ID: NCT05955001 Active, not recruiting - Clinical trials for Erectile Dysfunction

Efficacy of Tadalafil (5mg) For Treatment of Early Storage Symptoms and Erectile Dysfunction After Endoscopic Enucleation of Prostate

Start date: April 1, 2023
Phase: Phase 2/Phase 3
Study type: Interventional

From previous studies, the investigators found that sexual outcomes after prostate surgery may show insignificant improvement, remain unchanged or deteriorate in non-negligible number of patients especially those with high preoperative IIEF scores. Deterioration of erectile function could be attributed to persistence of storage symptoms specially nocturia. Several pathophysiologic mechanisms, described before, are involved in pathogenesis of LUTS and ED and one can imagine that after relief of obstruction, the erectile function should improve, however lack of improvement or even deterioration suggests that damage associated with these mechanisms is irreversible and patients may require some sort of penile rehabilitation after surgery. The investigators hypothesized that Tadalafil may enhance relief of storage symptoms and enhance recovery of erectile function after surgery for BPH. With this assumption, a RCT was designed to examine the utility and efficacy of Tadalafil, once daily dose, to relieve persistent/ de novo storage symptoms and early erectile function deterioration after endoscopic prostate surgery.

NCT ID: NCT05415748 Active, not recruiting - Clinical trials for Benign Prostatic Hyperplasia

Deprescribing Tamsulosin in Older Men

PERSONAL
Start date: September 18, 2021
Phase: Phase 4
Study type: Interventional

This is a pilot 12-week randomized, placebo-controlled N-of-1 deprescribing trial among older men receiving chronic tamsulosin therapy for lower urinary tract symptoms attributed to benign prostatic hyperplasia.

NCT ID: NCT05356260 Active, not recruiting - Clinical trials for Lower Urinary Tract Symptoms

Self-management Compared to Care-as-usual for Men With Lower Urinary Tract Symptoms

Start date: April 8, 2022
Phase: N/A
Study type: Interventional

Research question: Does offering an online self-management program lead to more efficient use of care by men with urinary complaints? Hypothesis: Many men with urinary symptoms receive medication from their GP. Advice on how to self-manage complaints is often skipped. This while self-management is effective. By offering self-management instead of visiting a GP the use of care by men with urinary complaints may decrease and treatment may become more efficient. Study design: Men are randomized to receive either care-as-usual by their GP or the online self-management program. Men will be followed for six months and the cost-effectiveness of the online self-management intervention will be compared to the care-as-usual

NCT ID: NCT05186740 Active, not recruiting - Clinical trials for Benign Prostatic Hyperplasia With Symptomatic Lower Urinary Tract Symptoms

ProVee Urethral Expander System IDE Study (ProVIDE)

ProVIDE
Start date: June 9, 2022
Phase: N/A
Study type: Interventional

A study to evaluate the safety, performance, and effectiveness of the ProVee Urethral Expander System (Investigational Device) when used in subjects with symptomatic urinary obstruction related to benign prostatic hyperplasia (BPH).

NCT ID: NCT04987138 Active, not recruiting - Clinical trials for Lower Urinary Tract Symptoms (LUTS)

Safety and Effectiveness Study of the Zenflow Spring System

BREEZE
Start date: September 30, 2021
Phase: N/A
Study type: Interventional

Evaluate the safety and effectiveness of the Zenflow Spring System in relieving LUTS associated with BPH.