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An Algorithm to Decide on Antibiotic Prescription in Lower Respiratory Tract Infection in Primary Care — UltraPro  

Lower Resp Tract Infection Clinical Trial

Official title:
Procalcitonin and Lung Ultrasonography Point-of-care Testing to Decide on Antibiotic Prescription in Patients With Lower Respiratory Tract Infection at Primary Care Level: Pragmatic Cluster Randomized Trial

Clinical Trial Summary

The study is randomized clustered pragmatic trial whose objective is to decrease unnecessary antibiotic prescription in adult patients with lower respiratory tract infection managed at primary care level in Switzerland, using a simple algorithm based on 2 point of care test results

Clinical Trial Description

The study will have two distinct phases:

The first phase will test the feasibility of the intervention (UltraPro) along a pilot study. Following the setup of a lung ultrasound training curriculum for general practitioners, the practicality of the whole UltraPro algorithm will be evaluated at primary care level.

The second phase will be a pragmatic randomized three-arm intervention study using an algorithm based on the results of procalcitonin and lung ultrasound to manage patients with lower respiratory tract infections at primary care level. The procalcitonin-ultrasound algorithm will be compared to procalcitonin-guided management alone and usual care. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03191071
Study type Interventional
Source Centre Hospitalier Universitaire Vaudois
Contact
Status Completed
Phase N/A
Start date September 1, 2018
Completion date April 30, 2020
View Details
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