Low-grade Inflammation Clinical Trial
Official title:
Probiotics Against Low Grade Inflammation and Increased Intestinal Permeability in the Elderly.
Verified date | April 2018 |
Source | Probi AB |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The purpose of this study is to evaluate the ability of a blend of berries and probiotics in reducing low-grade inflammation and intestinal permeability in the elderly. The intervention period is one month. Blood and fecal samples will be collected for analysis at baseline and at the end of the intervention with the aim to analyse possible changes in different parameters at the two timepoints. The participants will also be asked to keep a study diary throughout the study period for the documentation of their intestinal health and as a means for checking compliance.
Status | Completed |
Enrollment | 66 |
Est. completion date | December 4, 2015 |
Est. primary completion date | December 2015 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 75 Years to 90 Years |
Eligibility |
Inclusion Criteria: - Age >75 years - CRP 2-10 mg/L - Ability to fill in a study diary by him/herself Exclusion Criteria: - Intake of antibiotic treatment in the last 4 weeks before inclusion into the study. - Currently on corticosteroid treatment - Presence of chronic inflammatory disease |
Country | Name | City | State |
---|---|---|---|
Sweden | Lund University | Malmö |
Lead Sponsor | Collaborator |
---|---|
Probi AB | Lund University |
Sweden,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Reduced intestinal permebility measured as decline in the levels of zonulin in blood samples | All blood markers analysed in the study will be measured at start, before the onset of intervention and 4 weeks later at the end of intervention. |
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