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Low Blood Pressure clinical trials

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NCT ID: NCT06319248 Recruiting - Sepsis Clinical Trials

Use of Midodrine in Septic Shock Patients

Start date: June 12, 2024
Phase: Phase 2/Phase 3
Study type: Interventional

This study is being done to determine if early administration of Midodrine can improve outcomes by maintaining a higher mean blood pressure off of intravenous medications. Researchers want to see if Midodrine can help people with sepsis need fewer vasopressors, which could mean shorter hospital stays, less time with uncomfortable tubes, and a smoother recovery overall.

NCT ID: NCT05971121 Recruiting - Sedation Clinical Trials

Comparing Ciprofol and Propofol for Sedation in Hypotensive ICU Patients: a Single Center Prospective Cohort Study

Start date: October 1, 2022
Phase:
Study type: Observational

This study was a single-center, prospective, 2-year observational cohort study. The study subjects were ICU patients requiring vasopressor drugs and requiring sedation. According to the use of ciprofol or propofol in the treatment plan (determined by the doctor in charge according to the condition of the subjects), they were divided into groups: ciprofol group and propofol group. A total of 456 subjects were planned to be enrolled, including 304 subjects in the cyclopofol group and 152 subjects in the propofol group. The data of this study were obtained by extracting the routine clinical diagnosis and treatment records of the enrolled subjects.

NCT ID: NCT04082819 Completed - Hypertension Clinical Trials

MediBeat - HeartBeat Observation Trial

Start date: October 4, 2019
Phase: N/A
Study type: Interventional

The goal of the study was to compare the current gold standard blood pressure instrument (a mercury-filled sphygmomanometer with cuff and stethoscope) with the new experimental algorithm developed by HeartBeat Technologies Ltd. To that end, participants were recruited from Markham, Ontario and participated in a series of alternating blood pressure measurements over a period of 45 minutes. Comparisons were made between manual measurements and device measurements to determine the quality of the device readings. Measurements were taken by trained nurses and staff were consistent across the study duration.

NCT ID: NCT03182335 Active, not recruiting - Critical Illness Clinical Trials

Vasopressor SAT Study

Start date: April 28, 2014
Phase:
Study type: Observational

To assess the impact of daily awakening from sedation on the amount of vasoactive medication required in the ICU. The hypothesis of this proposal is that the amount of vasoactive drug required to maintain an adequate mean arterial blood pressure will be reduced during a daily awakening from sedation.

NCT ID: NCT02452125 Completed - Parkinsons Disease Clinical Trials

The Effects of Nicotine Chewing Gum in Parkinson's Disease

PD
Start date: May 2015
Phase: N/A
Study type: Interventional

The objective of this experiment is: To determine if nicotine chewing gum will improve acute episodes of orthostatic hypotension in PD subjects.

NCT ID: NCT01482559 Terminated - Hypotension Clinical Trials

Management of Hypotension In the Preterm Infant

HIP
Start date: February 2015
Phase: Phase 3
Study type: Interventional

The HIP trial is a large pragmatic, multinational, randomised trial of two different strategies for the management of hypotension in extremely low gestational age newborns (Standard with dopamine versus a restricted with placebo approach). HYPOTHESIS: A restricted approach to the management of hypotension in extremely low gestational age newborns will result in improved neonatal and long-term developmental outcomes. PRIMARY OBJECTIVE: To determine whether a restricted approach to the management of hypotension compared to using dopamine as first line pressor agent in infants born less than 28 weeks of gestation within the first 72 hrs after birth (transitional period), improves survival without significant brain injury at 36 weeks postmenstrual age (PMA) and improves survival without moderate or severe neurodevelopmental disability at 2 years corrected age.

NCT ID: NCT00576524 Terminated - Clinical trials for End Stage Renal Disease

Application of Impedance Threshold Device Technologies to Treat and Prevent Hypotension During Dialysis

ITD
Start date: September 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the application of the impedance threshold device during hemodialysis in children to optimize fluid removal, reduce the incidence of complications (such as cramps,vomiting and hypotension), and device tolerance.