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Low Back Pain clinical trials

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NCT ID: NCT01631513 Withdrawn - Pain Clinical Trials

An Open-label Evaluation of Tapentadol Extended Release (ER) in Participants With Moderate to Severe Chronic Pain After Conversion From Hydrocodone, Oxycodone Controlled Release (CR), and/or Morphine Sustained Release (SR)

Start date: August 2012
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate tapentadol Extended Release (ER) in the treatment of moderate to severe chronic pain in participants with a diagnosis of chronic low back pain (LBP) or osteoarthritis (OA) of the hip or knee after conversion from hydrocodone, oxycodone Controlled Release (CR), and/or morphine Sustained Release (SR).

NCT ID: NCT01587508 Withdrawn - Acute Lumbago Clinical Trials

Study Comparing A New Drug Containing The Combination Meloxicam And Cyclobenzaprine In The Treatment Of Acute Lumbago

Start date: May 2013
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the efficacy end tolerability of a new drug containing the combination meloxicam and cyclobenzaprine (7,5/10mg) and the same components alone in the treatment of acute lumbago.

NCT ID: NCT01431742 Withdrawn - Pain Clinical Trials

Longterm Safety Study of BEMA Buprenorphine in Subjects With Chronic Low Back Pain

Start date: July 2012
Phase: Phase 3
Study type: Interventional

This is an open label study of up to approximately 52 weeks duration to assess the safety and effectiveness of BEMA Buprenorphine in the management of moderate to severe chronic low back pain. BEMA Buprenorphine is an oral transmucosal form of the opioid analgesic, buprenorphine hydrochloride, intended for application to the buccal mucosa. Buprenorphine is a synthetic opioid that is classified as a partial μ-receptor agonist and a Schedule III controlled substance in the United States.

NCT ID: NCT01298466 Withdrawn - Low Back Pain Clinical Trials

Primary Care Identification Of Patients With Chronic Neuropathic Low Back Pain Study

PINPOINT
Start date: February 2012
Phase: Phase 4
Study type: Interventional

A0081256 is a prospective, open-label, multi-centre European study designed to raise awareness and enhance the diagnosis of patients with chronic low back pain with a neuropathic pain component in primary care who are refractory to standard analgesic therapy and/or one treatment for neuropathic pain and evaluate the effectiveness and tolerability of pregabalin in this population. The impact of pregabalin on analgesia, patient satisfaction with treatment, patient anxiety and depression, sleep interference, physical functioning and work productivity will be assessed.

NCT ID: NCT01095783 Withdrawn - Clinical trials for Chronic Low Back Pain

Treatment of Low Back Pain in Patients With End-stage Renal Disease on Hemodialysis

Start date: March 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether a physiotherapeutic intervention is effective in the treatment of low back pain in hemodialysis patients

NCT ID: NCT01089491 Withdrawn - Low Back Pain Clinical Trials

Study of Cells From Spinal Cavity of Patients With Low Back Pain

Start date: March 2010
Phase: N/A
Study type: Observational

The purpose of this study to determine if cells collected give us information about what is causing a patient pain can be detected and connected with epiduroscopy images (pictures taken with a small fiber optic scope). We want to determine if abnormal areas are the source of that pain by using a catheter to provide a brief, low intensity electrical stimulation. We also want to determine if there are cells in the epidural cavity (area surrounding the spinal cord) of patients who have low back pain with or without pain shooting down one or both legs that provide information about what is causing the pain.

NCT ID: NCT01077947 Withdrawn - Low Back Pain Clinical Trials

Value of Functional Anesthetic and Provocative Discography in the Surgical Treatment of Discogenic Pain

Start date: February 2010
Phase: Phase 4
Study type: Interventional

Although discography and spinal imaging techniques, either alone or in combination, are commonly used to diagnose discogenic pain, their exact role in predicting surgical results are poorly defined. Our aim in this study is to compare the ability of Functional anesthetic discography (FAD), and Provocative Discography (PD) to diagnose discogenic pain and to correctly identify the disc levels for the surgical treatment. Proper identification for disc levels should improve the overall results of surgery for this condition. Patients with discogenic pain have better outcomes if the disc levels for the fusion surgery are identified by using FAD compared to similar disc level identification by PD.

NCT ID: NCT00704210 Withdrawn - Low Back Pain Clinical Trials

Effectiveness of Mechanical Decompression for Low Back Pain Relief

SpiDERS
Start date: August 2006
Phase: N/A
Study type: Interventional

Objective To demonstrate the effectiveness of a conservative treatment approach for chronic low back pain that addresses the underlying problem of intervertebral disc lesions and degenerative disc disease, namely vertebral pressure on vital structures of the lumbar region.

NCT ID: NCT00666419 Withdrawn - Low Back Pain Clinical Trials

Prevalence of Back Pain and Associated Risk Factors in 10-12 Year Old Schoolchildren

Start date: September 2006
Phase:
Study type: Observational

A large study in Mallorca, Spain showed that nonspecific low back pain is quite prevalent in adolescents 13-15 years of age (Kovacs, 2003). Since below the age of seven years hardly any child has suffered low back pain, the purpose of this study is to determine the prevalence of low back pain in children 10-12 years of age, and to investigate the risk factors associated with its occurrence.

NCT ID: NCT00469118 Withdrawn - Low Back Pain Clinical Trials

Clinical Efficacy and Safety of Axiom Worldwide DRX9000 Axial Decompression System for Treatment of Low Back Pain

Start date: February 2009
Phase: Phase 2
Study type: Interventional

This study will document efficacy and safety of the Axiom Worldwide DRX9000™ for treatment of low back pain (LBP) in a prospective, randomized, crossover, multicenter trial utilizing a standardized clinical research multimodal protocol. During the first two weeks subjects are randomized to receive either conservative care or DRX treatment first and then cross over to receive either conservative care or DRX treatment the next 6 weeks. This study will test the hypothesis that standardized 6-week treatment regimen of spinal decompression using DRX9000™ will reduce chronic lower back pain more than conservative therapy (current baseline therapy).