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Low Back Pain clinical trials

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NCT ID: NCT04791891 Recruiting - Low Back Pain Clinical Trials

Quebec Low Back Pain Study: Core Dataset

QLBPS
Start date: November 1, 2018
Phase:
Study type: Observational

Persistent back pain is the leading cause of years lived with disability worldwide. Current therapeutic interventions are often either not effective or are associated with undesired consequences. These concerns are further amplified by the current opioid epidemic, resulting in an enormous public health crisis. Experts from diverse disciplines including molecular/cellular biology, neuroscience, psychology and public health formed the Quebec Back Pain Consortium to address this challenge. The overall goal of this project is to facilitate research on factors that contribute to the persistence and recovery from back pain. To accomplish this goal, we will recruit individuals suffering from acute and chronic low back pain across the province of Quebec and follow their pain trajectories over two years using an online platform. During that period, satellite projects will investigate specific risk factors including genetics, diet and physical activity, and advanced statistical methods will be used to integrate and interpret the data. A better understanding of factors influencing back pain will eventually allow for improved early intervention, interruption and prevention.

NCT ID: NCT04783454 Recruiting - Low Back Pain Clinical Trials

Preventing Neck & Back Pain in Teleworking Office Workers: a Randomized Controlled Trial

Prevent@HOME
Start date: November 12, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the effect of a general training program and educational session to prevent neck and/or low back pain in desktop workers

NCT ID: NCT04772950 Recruiting - Low Back Pain Clinical Trials

Measuring Deep and Superficial Multifidus and the Activation Pattern During Dynamic Task Correlating With Trunk Stability Ability and Functional Performance in Different Ages Asymptomatic and Unspecific Low Back Pain Adult

Start date: March 8, 2021
Phase:
Study type: Observational

The first propose of the study is to understand the contraction of deep and superficial multifidus in patients with non-specific low back pain and the elderly. The second purpose of the study is to understand the relationship between the multifidus and the functional performance in patients with non-specific low back pain and the elderly. The hypothesis is that the patients with non-specific low back pain and the elderly have less ability to contract the deep multifidus then asymptomatic adults and younger adults. Besides, the multifidus is correlated to the functional performance.

NCT ID: NCT04770480 Recruiting - Chronic Pain Clinical Trials

Non-pharmacological Treatment for Pain After Spine Surgery

Start date: December 10, 2021
Phase: N/A
Study type: Interventional

This study will compare the effectiveness of two pain management pathways (standard vs. enriched) for patients undergoing lumbar spine surgery in the Military Health System (MHS). Effectiveness will be based on post-surgery patient-centered outcomes and extent of opioid use. The study design is a 2-arm, parallel group, individual-randomized trial.

NCT ID: NCT04757740 Recruiting - Low Back Pain Clinical Trials

Comparison Between Platelet-rich Fibrin and Steroid for Intra-articular Injection for Sacroiliac Joint Dysfunction

Start date: March 1, 2021
Phase: Phase 4
Study type: Interventional

Low back pain is one of the commonest complaints nowadays affecting nearly 20% of the population, Sacroiliac joint has been accused of being the primary cause of pain in about 10%: 27% of this population. The sure diagnosis of sacroiliac joint pain is challenging because of multiple crossed factors of facet joint pain and intervertebral disc pain. Diagnosis can be done by history taking, local examination, imaging techniques, and controlled local anesthetic blocks. Controlled local anesthetic blocks are diagnostic and therapeutic done by various methods either landmark-guided or imaging-assisted either by fluoroscopy, computed tomography (CT), magnetic resonance (MRI), or ultrasound-guided. Lower cost, real-time viewing of needle leading to higher accuracy rate, and low ionizing radiation dose are favoring ultrasound-guided injection over other modalities. Numerous treatment modalities are being used for sacroiliac joint pain ranging from physiotherapy and systemic analgesics like Non-steroidal anti-inflammatory drugs (NSAIDs) to minimally invasive intra-articular, periarticular injection, radiofrequency neurotomy, and surgical fusion of the joint. Multiple injectates are being used for intraarticular injection most commonly local anesthetics and steroids which offer short-term symptomatic relief and delay the degenerative process. The need for a longer duration effect directly affects the disease process itself aiming for accelerating the joint healing rate by biological growth factors found in human blood especially in platelets. Platelet-rich plasma (PRP) has been used aiming to inject a high concentration of growth factors directly into the joint. Platelet-rich fibrin (PRF), the second generation of platelet-rich plasma is now tried having the advantage of a simpler preparation and higher values of growth factors.

NCT ID: NCT04747860 Recruiting - Low Back Pain Clinical Trials

Predictors of Work Resumption After Back Surgery

WABS
Start date: February 23, 2021
Phase:
Study type: Observational [Patient Registry]

This prospective, longitudinal study aims to identify modifiable predictors of return to work after back surgery.

NCT ID: NCT04747314 Recruiting - Clinical trials for Chronic Low Back Pain

Treating Negative Affect in Low Back Pain Patients

TNA-LBP
Start date: March 31, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

This study will examine how the use of antidepressant, physical therapy, and combination of both affects pain, function, and depression outcomes in chronic low back pain patients.

NCT ID: NCT04744883 Recruiting - Clinical trials for Chronic Low-back Pain

Efficacy of Spinal Manipulation Therapy or Mindfulness-based Reduction Therapy on Patients With Chronic Low Back Pain

Start date: August 10, 2020
Phase: Early Phase 1
Study type: Interventional

Chronic Pain Management (CPM) has increasingly utilized long-term opioid analgesic therapy, a change associated with increased opioid abuse (a greater exposure in vulnerable individuals), non-pain health consequences (hormone changes, falls), and a dramatic rise in opioid-related overdoses and deaths. Treatment strategies that minimize the need for chronic high-dose opioids are sorely needed. This project will aim to test what degree mindfulness therapy (MT) and spinal manipulation therapy (SMT) produce pre- to mid- to post-treatment changes in endogenous opioid (EO) function.

NCT ID: NCT04734314 Recruiting - Clinical trials for Chronic Non-Specific Low Back Pain

Efficacy of Vojta on Balance and Quality of Life in Subject With CNLBP

Start date: April 1, 2020
Phase: N/A
Study type: Interventional

. To investigate the effect of Vojta method on static balance ,dynamic balance, quality of life in patients with chronic non - specific low back pain

NCT ID: NCT04730700 Recruiting - Clinical trials for Chronic Low-back Pain

Evaluation of Multi-Tined Expandable Electrode (MEE) Efficacy and Safety in Treatment of Lumbar Facet Arthropathy by Radiofrequency Neurotomies Compared to Conservative Medical Management.

MEE
Start date: December 17, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to better understand how people feel after a radiofrequency ablation standard of care surgery using a different type of needle (multi-tined expandable electrode/MEE) in comparison to receiving conventional medical management (CMM) techniques.