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Low Back Pain clinical trials

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NCT ID: NCT02836509 Not yet recruiting - Low Back Pain Clinical Trials

Comparison of Intravenous Ibuprofen and Paracetamol in Patients With Low Back Pain Presented to the Emergency Department

Start date: September 2016
Phase: Phase 4
Study type: Interventional

Currently, Paracetamol and Ibuprofen are widely used by emergency physicians in Turkey for the pain treatments. The objective of the study was to assess whether intravenous Paracetamol has superior Low Back Pain reduction will compare with Ibuprofen in emergency department (ED) adults. Half of the participants will receive Paracetamol and the other half will receive Ibuprofen.

NCT ID: NCT02782286 Not yet recruiting - Low Back Pain Clinical Trials

Morphine Versus Ketorolac in Low Back Pain

Start date: May 2016
Phase: Phase 4
Study type: Interventional

The study is prospective, double blinded, randomised controlled and has the purpose to compare the analgesic effects of ketorolac or morphine intravenous in low back pain.

NCT ID: NCT02774694 Not yet recruiting - Chronic Pain Clinical Trials

Prediction of Outcome of Interventional Pain Management

POINTPM
Start date: January 2026
Phase:
Study type: Observational

Interventional pain management for back and neck pain is widely used, but the indications and relative merits of these techniques rest subject to discussion. This study aims to identify prognostic criteria for patients who might specifically benefit from interventional pain management. Specifically, the nociceptive reflex threshold will be investigated, which is a measure of central sensibilisation and thus a potentially important prognostic factor.

NCT ID: NCT02759757 Not yet recruiting - Clinical trials for Chronic Low Back Pain

Is Kinesio Taping Able to Influence the Electrical Activity of Muscles in Patients With Low Back Pain?

Start date: May 2016
Phase: N/A
Study type: Interventional

Objectives: To test if the Kinesio Tex Gold ® is able to change the electromyographic signal of iliocostalis and longissimus muscles in patients with chronic nonspecific low back pain. Study design: Three-arm, randomized controlled trial with a blinded assessor. Location of study: Physical therapy Clinic of the Universidade Cidade de São Paulo (UNICID) Patients: Sixty-three patients with chronic nonspecific low back pain. Intervention: Patients allocated to the Kinesio Taping® group will receive the tape as described by the manufacturer's manual. The patients assigned to the placebo group will receive a Micropore tape and the control group will not receive any intervention. All groups will be assessed before and 30 minutes after intervention Measures: The following outcomes will be measured: 1) Muscle activity and 2) pain intensity. Limitations: Therapists will not be blinded.

NCT ID: NCT02703402 Not yet recruiting - Low Back Pain Clinical Trials

Effects of an Exercise Program Under Supervision and Unsupervised in the Treatment of Low Back

Start date: March 2016
Phase: N/A
Study type: Interventional

ABSTRACT: Low back pain is one of the most frequent causes of incapacity. The prevalence of this syndrome is 60-85% for the survival of the individuals. Among the most promising strategies of low back pain intervention, is the physical activity that is usually associated with a long list of health benefits.

NCT ID: NCT02615418 Not yet recruiting - Clinical trials for Chronic Low Back Pain (CLBP)

Non Invasive Brain Stimulation Treatment for CLBP

NIBSTCLBP
Start date: January 2016
Phase: N/A
Study type: Interventional

This trial is designed to preliminary evaluate the efficacy and safety of NIBS system for treatment of chronic low back pain (CLBP) (over 6 months). The trial is of a double blind sham controlled partial crossover design and will involve 2 weekly treatments and evaluations for 6 weeks, with 6 weeks follow-up. The goal of the study is to 1. Asses the CLBP change immediate and long term effect for the trial duration and follow-up. 2. Asses quality of life improvement as measure by sleep quality and questioners. 3. Asses long term neuronal changes or lack thereof in treated and untreated subjects.

NCT ID: NCT02393391 Not yet recruiting - Clinical trials for Chronic Low Back Pain

A Novel Non Invasive Brain Stimulation Based Treatment for Chronic Low Back Pain (CLBP)

Start date: May 2015
Phase: Phase 2/Phase 3
Study type: Interventional

Neuropathic pain results from damage to or dysfunction of the peripheral or central nervous system, rather than stimulation of pain receptors. Diagnosis is suggested by pain out of proportion to tissue injury, dysesthesia (eg, burning, tingling), and signs of nerve injury detected during neurologic examination. Although neuropathic pain responds to opioids, treatment is often with adjuvant drugs (eg, antidepressants, anticonvulsants, baclofen, topical drugs). Neuropathic pain (e.g. phantom limb pain, CRPS, postherpetic neuralgia, postsurgical pain syndromes, CLBP etc.) remains a challenging condition to treat because it is commonly refractory to classical pharmacological and to surgical treatment approaches. Chronic low back pain (CLBP) is a widespread and costly problem for which few interventions are effective. An increased focus on the study of the nervous system and its involvement in pain disorders has documented complex neuronal activity and structural changes at a peripheral, as well as at spinal cord and cortical levels indicating a neuropathic element in CLBP. Accumulated evidence suggests that neuropathic pain in general and CLBP specifically might be associated to brain cortical plastic changes. Thus an ideal rehabilitative approach should aim to reverse them. In line with this idea, the investigators suggest an innovative noninvasive intervention aimed at alleviating neuropathic pain. New rehabilitative approaches have been proposed to try and reverse this cortical reorganization. Results of several studies have shown that motor cortex stimulation with epidural electrodes or repetitive transcranial magnetic stimulation (rTMS) or transcranial direct stimulation (tDCS) are effective in reducing pain in patients with central pain refractory to treatment. Transcranial direct current stimulation (tDCS) is an easily applied and safe technique by which brain activity can be modulated noninvasively and can decrease pain in patients with refractory central pain. The investigators hypothesized that focal-tDCS treatment personally customized to each patients basal neuronal network properties would result in both acute and long term pain relief for neuropathic pain patients.

NCT ID: NCT02150096 Not yet recruiting - Clinical trials for Chronic Low Back Pain

Laser and Therapeutic Ultrasound in the Management of the Chronic Non-specific Low Back Pain

Start date: May 2014
Phase: N/A
Study type: Interventional

The objective of this study is evaluate the laser and ultrasound effect on pain and disability in women with non-specific chronic low back pain.

NCT ID: NCT02115009 Not yet recruiting - Clinical trials for Chronic Low Back Pain

The Sacroiliac Joint With SIJ Nerve Entrapments and Chronic Low Back Pain

SARA31143
Start date: June 2014
Phase: N/A
Study type: Observational

The overall goal of this study is to characterize the SIJ form, function, nerve entrapments, lumbo-pelvic configuration and their possible relationships with nonspecific chronic LBP in females and males. Specific aims: 1.To investigate the relationship between SIJ bridging and NSCLBP in females and males. 2. To investigate the prevalence and characterization of nerve entrapment of the lumbar sacral plexus around the SIJ in females and males. 3. To investigate the correlation between the lumbar sacral plexus nerve entrapments around the SIJ and NSCLBP in females and males. 4. To investigate the relationship between the lumbar sacral plexus nerve entrapments around the SIJ and lumbo-pelvic morphology in females and males. 5. To characterize the location and severity of articular degenerative changes in the SIJ and its relationship with lumbo-pelvic morphology in females and males. 6. To investigate the relationship between articular degenerative changes in the SIJ and LBP in females and males.

NCT ID: NCT01979783 Not yet recruiting - Low Back Pain Clinical Trials

Correlation Between Electromyography and Thickness Change of the Trunk Muscles in Subjects With Low Back Pain

Start date: November 2013
Phase: N/A
Study type: Observational [Patient Registry]

Transversus abdominis (TrA) and lumbar multifidus (LM) muscle have been proposed to play key role in stability of the lumbosacral spine. The muscles' functional and/or structural deficits have been linked to the low back pain (LBP) syndrome. Evaluation of the transversus abdominis and lumbar multifidus muscles' function in clinical practice is scarce and not well defined due to number of reasons. Surface electromyography of TrA and LM muscles, as a method of examining muscles function, is not involved in clinical routine. Rehabilitative Ultrasound Imaging (RUSI) of the TrA and LM, apart from providing information about their morphology, could be helpful in assessing their function. Since concentric muscle contraction results in the shortening and thickening of the muscle, evaluation of the potential association between muscle's morphometry, assessed by the ultrasound, and electromyography, may be of potential clinical interest. However, this potential relationship is context-dependant. Our aim was to establish the difference in the thickness change of the TrA and LM muscle during activation in subjects with and without low back pain, and to establish the possible correlation between electromyography and the thickness change of these muscles assessed by ultrasound in both groups of subjects.