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Low Back Pain clinical trials

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NCT ID: NCT05754190 Recruiting - Chronic Pain Clinical Trials

Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA

Start date: June 20, 2023
Phase:
Study type: Observational

This study relies on the use of a smartphone application (SOMA) that the investigators developed for tracking daily mood, pain, and activity status in acute pain, chronic pain, and healthy controls over four months.The primary goal of the study is to use fluctuations in daily self-reported symptoms to identify computational predictors of acute-chronic pain transition, pain recovery, and/or chronic pain maintenance or flareups. The general study will include anyone with current acute or chronic pain, while a smaller sub-study will use a subset of patients from the chronic pain group who have been diagnosed with chronic low back pain, failed back surgery syndrome, or fibromyalgia. These sub-study participants will first take part in one in-person EEG testing session while completing simple interoception and reinforcement learning tasks and then begin daily use of the SOMA app. Electrophysiologic and behavioral data from the EEG testing session will be used to determine predictors of treatment response in the sub-study.

NCT ID: NCT05752396 Recruiting - Healthy Volunteers Clinical Trials

Overlapping Pain Trajectory Study

COPC
Start date: March 1, 2023
Phase:
Study type: Observational

The goal of this observational study is to learn about spatial and temporal nociceptive filtering in adolescents with chronic overlapping pain conditions (COPCs). The main questions it aims to answer are: 1. If spatial and temporal filtering of nociceptive information is disrupted in youth with COPCs compared with youth with localized pain conditions and healthy controls. 2. If disrupted nociceptive processing at baseline is associated with the transition from a single localized pain condition to COPCs in youth. Participation includes: - quantitative sensory testing - blood draw - sleep assessment - questionnaires

NCT ID: NCT05751499 Recruiting - Low Back Pain Clinical Trials

Diagnostic and Prognostic Blood Markers in Non Specific Low Back Pain

Start date: March 1, 2023
Phase:
Study type: Observational [Patient Registry]

• To compare the diagnostic and prognostic blood markers in acute and chronic nonspecific low back pain with healthy controls

NCT ID: NCT05748548 Recruiting - Clinical trials for Low Back Pain, Postural

Effects of Lumbal Lordosis and Thoracic Kyphosis Angles on Muscle Activations

Start date: March 22, 2023
Phase:
Study type: Observational [Patient Registry]

When the thoracic kyphosis and lumbar lordosis are within a normal range of angular values back pain is less likely to occur. Angular modifications in the physiological curvatures of this sagittal plane have been shown to indicate spinal disorders. For instance, increasing lumbar lordosis and thoracic kyphosis result in higher intradiscal pressure, tension in the spine's passive parts, and creep in the lumbar viscoelastic structures. One of the most important factors of human biomechanics, spinal curvatures provide optimal energy expenditure and movement capacity. Abnormal adaptations in thoracic and lumbar spine biomechanics can cause low back and back pain. Multiple spinal segments are covered by the lumbar erector spinae muscle (LES), which is regarded as a superficial back muscle. LES consists of two muscles, the longissimus thoracis and iliocostalis lumborum. To move the lumbar spine, the lumbar erector spinae muscle (LES) is recruited in a manner that depends on the applied force. It was suggested that patients used LES to compensate for laxity in passive ligamentous structures in an attempt to reduce excessive force on the lumbar spine. Excessive lumbopelvic movements and altered muscle activation patterns are common in patients with low back pain. Researchers have investigated the timing of each muscle's onset and the activity of the LES, and found that patients with low back pain had higher LES activation compared to healthy people. Exercises for strengthening the LES muscle have been performed trunk extension during prone position. Strenghening LES and thoracic extansors may lead to decrease or prevent painful spinal disorders, improve thoracic excessive kyphosis and other complications. Prone trunk extension exercises is used to clinically exercise approcah to activate weak and susceptible to fatigue LES muscle in patients with nonspecific low back pain. This exercise lead to not only strentghening but also lengthening and streching these muscles. To fully understand the effects and underliying the mechanism of this exercise, biomechanical changes in lumbopelvic movement patterns of individuals with kyphotic posture should be examined. Based on current evidence, it is not clear the mechanism that the prone trunk extension exercises is effective on different spinal alignment postures as excessive thoracic khyposis and compansation mechanism on lumbal lordosis. Thus findings from this research may guide clinicians to examine the effects of different prone trunk extension exercises on LES muscles activation. Mitani et al showed that different upper extremity postures effects the lumbal multifudis activations during standing. Brown et al indicated that sit-stand workstations do not change muscle activations of lumbar muscles. Muyor et al concluded that spinal aligment of cyclists affects core muscle activity during cyling. Wattananon et al demonstrated that clinicians should focus on muscle activation patterns rather than the amount of lumbopelvic motion during prone hip extension. Based on the current studies, and to optimally address the underlying mechanism that the main objective was to investigate and show the effects of lumbal lordosis and thoracic kyphosis angles on muscle activations during different low back exercises.

NCT ID: NCT05748509 Recruiting - Low Back Pain Clinical Trials

COMPARISON OF THE LUMBAR EXTANSOR MUSCLES' ACTIVATIONS

Start date: March 22, 2023
Phase:
Study type: Observational

Low back pain is a public health problem faced by 65-80% of the world's population at some point in their lives. Although the prognosis for low back pain is considered good, 80% of patients with acute low back pain recover within 6 weeks, and 7-10% of them have complaints that last longer than 3 months and become chronic, causing great labor and economic loss. A multidisciplinary approach is often required in the treatment of low back pain, which is one of the most common diseases in the society and one of the most expensive diseases in terms of both labor loss and treatment cost. In this approach, waist exercises and waist protection training are accepted as an effective and economical method. In our society, there is no conscious education and exercise habits about the techniques of protecting back health. Most patients with chronic low back pain initially ignore low back pain, but apply to health centers when symptoms related to low back pathology become severe. In many studies, it has been shown that strong waist and abdominal muscles and good physical condition reduce musculoskeletal damage in low back traumas. Most studies show that back extensors and flexors are of low strength in patients with low back pain compared to asymptomatic individuals. In the study conducted by Lee et al. on 3000 male workers, it was found that low back pain was lower in those with exercise habits. In a systematic review and meta-analysis conducted in 2017, it was reported that leisure time physical activity can reduce the risk of chronicity of nonspecific low back pain by 11-16%. When the literature is examined, it is seen that there are different exercise approaches recommended for the conservative treatment of low back pain. There are studies reporting that pilates is effective in terms of pain, disability, kinesiophobia, function, quality of life, flexibility and balance in patients with low back pain and that it has no harmful effects. In another study, it was reported that traditional Chinese exercises are effective in terms of pain, disability and cognitive function in low back pain, and interventions performed 1-2 times a week and 3-4 times a week are associated with reduced pain. Liu et al. In a study conducted in 2019 by Chen-style Tai Chi in individuals aged 50 years and older with chronic nonspecific low back pain, it was found that Chen style Tai Chi reduced pain but did not improve lower extremity proprioception. Wieland et al. showed that yoga led to small or moderate improvements in low back-related functions at three and six months, compared with non-exercise controls in chronic nonspecific low back pain. However, while there are only subjective measurements in the literature about which one is more effective, there is no evidence that includes objective measurements. For this purpose, in this study, the investigators aim to determine which of the different exercises recommended for low back pain contract the muscle more effectively and compare these measurements with anthropometric measurements.

NCT ID: NCT05741645 Recruiting - Low Back Pain Clinical Trials

Effect of Elastic Taping on Stiffness of Lumbar Stabilizer Muscles

Start date: June 20, 2023
Phase: N/A
Study type: Interventional

Low back pain is a common health problem worldwide. Epidemiological studies have shown that 70-80% of all people are affected at least once in their lifetime. Although it is common, often the cause of the pain has not been determined and is called 'nonspecific low back pain. Chronic low back pain ranks second among the most common pain complaints under the age of 45 in the industrial age of limited activity. Organic pathology is not encountered in most musculoskeletal system pains. There are usually many underlying causes. The current literature offers a variety of treatment options, depending on the duration and severity of the symptoms of non-specific low back pain. These treatments include behavioral cognitive therapy, medication, electrophysical agents, manual therapy, and general exercises. Looking at the literature, it has been observed that there are not many objective studies investigating the effect of elastic bandage application on muscle elasticity. 'Shear Wave Elastography' is a method that quantitatively reveals the elasticity of tissues by measuring the speed of shear waves formed in the tissues through non-invasive high-frequency ultrasound waves. In recent studies, Shear Wave Elastography has shown promising results in demonstrating the elasticity of peripheral nerves.

NCT ID: NCT05736393 Recruiting - Low Back Pain Clinical Trials

Translation of Robotic Apparel for Alleviating Low Back Pain

Start date: March 15, 2024
Phase: N/A
Study type: Interventional

This is a NIAMS-sponsored clinical trial being conducted through the NIH Helping to End Addition Long-term (HEAL) Initiative's Back Pain Consortium (BACPAC) Research Program. This is a single-arm controlled trial with individuals aged 18-70 with low back pain (LBP). This study investigates the effect(s) of augmenting physical therapy (PT) interventions with the use of an experimental wearable soft robotic device ('exosuit').

NCT ID: NCT05724160 Recruiting - Low Back Pain Clinical Trials

Using Non-Weightbearing Stationary Elliptical Machines for Patients With Chronic Low Back Pain

Cubii
Start date: September 18, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to assess the effect of non-weightbearing stationary ellipticals (Cubii, Fitness Cubed, Inc.) on patient well-being with chronic lower back pain (CLBP). The main questions it aims to answer are: 1. Assess the effect of non-weightbearing stationary ellipticals on clinical outcomes inclduing vital signs, pain, disability, analgesic use, mental health, abdominal muscle strength, and compliance in patients with CLBP. 2. Assess the effect of placing the patients into an interactive virtual environment during the exercise sessions on the outcomes of the program Participants will participate in 60 minute training sessions to see if there are effects to their CLBP.

NCT ID: NCT05721027 Recruiting - Low Back Pain Clinical Trials

Ibuprofen With or Without Dexamethasone for Acute Radicular Low Back Pain.

Start date: July 5, 2023
Phase: Phase 4
Study type: Interventional

This will be a placebo controlled, randomized, double-blind, comparative effectiveness study, in which we patients are enrolled during an emergency department (ED) visit for acute radicular low back pain (LBP) and followed by telephone two and seven days later. Patients will be randomized to receive an oral dose of dexamethasone for 2 consecutive days or placebo during an ED visit for acute radicular LBP. Every patient will receive a 7 day supply of ibuprofen and a low back pain education session.

NCT ID: NCT05718713 Recruiting - Clinical trials for Chronic Low-back Pain

Respiration in Chronic Low Back Pain

Start date: January 30, 2023
Phase:
Study type: Observational

The goal of this observational study is to learn about respiratory muscle strength, respiratory functions, and balance in patients with chronic low back pain.