A Long-term Survival Analysis of Different Surgical Method in Early Hepatocellular Carcinoma

Long-term Effects of Cancer Treatment Clinical Trial

Official title: Long-term Survival Analysis of Robotic, Laparoscopic and Open Liver Resection for Hepatocellular Carcinoma in BCLC Stage 0-A: A Prospective Cohort Study With Matched Comparison

Status Completed

Clinical Trial Summary

The investigators established three prospective cohorts of patients with BCLC stage 0-A HCC, based on different surgical approaches (open, laparoscopic and robotic). After 5 years of follow-up, the investigators used propensity score matching (PSM) to reduce selection bias and then compared the long-term oncological outcomes of the three different surgical approaches, which might provide high-level evidence in non-randomized observational studies.

Clinical Trial Description

In this study, three prospective cohorts of patients with BCLC stage 0-A HCC, underwent complete liver resection using different surgical approaches (OLR, LLR, and RALR), were established. After adequate periods of follow-up, the long-term oncological outcomes of the three different surgical approaches were compared, providing a higher level of evidence using a non-randomized comparative study based on propensity score matching (PSM) analysis. ;

Related Conditions & MeSH terms

• Carcinoma, Hepatocellular
• Long-term Effects of Cancer Treatment

• NCT number: NCT05117047
• Study type: Observational [Patient Registry]
• Source: Tongji Hospital
• Status: Completed
• Start date: February 14, 2015
• Completion date: June 30, 2021