Clinical Trials Logo

Clinical Trial Summary

This study will test the effectiveness of addition of Sodium Bicarbonate as a buffering agent to the anaesthetic solution on minimizing the pain of injection and increasing the onset time and potency of the anaesthetic solution in children


Clinical Trial Description

27 healthy cooperative children will be enrolled in the study after taking their guardians' informed consent. The study design will be a split mouth design where each patient will be received buffered anaesthetic solution (8.4% sodium bicarbonate will be added to the anaesthetic solution in ratio 1:19) in one side and conventional anaesthetic solution (4% articaine HCL with 1:1000000 epinephrine) in the other side. The pain during injection for each patient in both sides will be then compared using objective and subjective methods. The onset time of the anaesthesia in both sides will also be compared for each patient using Transcutaneous electric nerve stimulator device (TENS) The results will be collected and mentioned. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05473819
Study type Interventional
Source Alexandria University
Contact
Status Active, not recruiting
Phase N/A
Start date May 15, 2022
Completion date September 1, 2022

See also
  Status Clinical Trial Phase
Completed NCT04633850 - Implementation of Adjuvants in Intercostal Nerve Blockades for Thoracoscopic Surgery in Pulmonary Cancer Patients
Completed NCT03262857 - Effect of Lidocaine With Magnesium Sulfate on the Success of the Inferior Alveolar Nerve Block Phase 2
Withdrawn NCT03502135 - Efficacy of Tetracaine/Oxymetazoline Nasal Spray for Endodontic Treatment Phase 4
Not yet recruiting NCT02535273 - The Effect of Dexmedetomidine Analgesia and Sedation in Minimally Invasive Spine Surgery Under Local Anesthesia Phase 4
Not yet recruiting NCT05902780 - Can Caudal Dexmedetomidine Provide Effective Analgesia? N/A
Completed NCT04885777 - Topical Lidocaine Anesthesia for Nasopharyngeal Sampling N/A
Recruiting NCT04086394 - PECS Block in Partial Mastectomy for Postoperative Pain Control N/A
Recruiting NCT06129162 - Pain Perception Comparison of Computerized vs Conventional Injection Methods N/A
Completed NCT02922504 - Impact of Music Intervention on Pain Control In First Trimester Surgical Abortion Under Local Anesthesia N/A
Completed NCT00539084 - A Study to Assess the Safety and Efficacy of a Microneedle Device for Local Anesthesia N/A
Completed NCT03176446 - Pain and Anxiety Evaluation in Children Using Different Techniques of Local Anesthesia for Dental Treatment N/A
Completed NCT04947267 - To Compare the Pulpal Oxygen Saturation Level After Administering Mepivacaine With and Without Vasoconstrictor Phase 2
Completed NCT02825225 - A Prospective Randomized Trial of Two Different Prostate Biopsy Schemes N/A
Completed NCT01360749 - Efficacy and Safety of Lambdalina (Lidocaine Cream) Versus Placebo as an Anesthetic for Laser Hair Removal Phase 2
Completed NCT00889642 - Safety and Efficacy Study of an Iontophoretic Patch Containing Lidocaine and Epinephrine for Venipuncture in Healthy Adult Volunteers Phase 2
Not yet recruiting NCT06395987 - Result Of Use Of Wide Awake Local Anaesthesia In Fixation Of Ankle Fractures
Completed NCT04653974 - Pain Perception of Needle-free System N/A
Completed NCT02884596 - Success of Inferior Alveolar Nerve Block in Women Taking Selective Serotonin Reuptake Inhibitors
Completed NCT02440347 - Effects of Articaine Computer-controlled and Conventional Delivery for Anterior and Middle Superior Alveolar Nerve Block Phase 4
Completed NCT02371759 - Lidocaine + Clonidine for Intraoral Anesthesia in Patients With Diabetes Mellitus Type 2 Phase 3