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Effectiveness of Sodium Bicarbonate Buffered Anaesthetic Solution on Pain During Injection

Local Anesthesia Clinical Trial

Official title:
Effectiveness of Sodium Bicarbonate Buffered Anaesthetic Solution on Pain During Inferior Alveolar Nerve Block in Children : a Randomised Controlled Clinical Trial

Clinical Trial Summary

This study will test the effectiveness of addition of Sodium Bicarbonate as a buffering agent to the anaesthetic solution on minimizing the pain of injection and increasing the onset time and potency of the anaesthetic solution in children

Clinical Trial Description

27 healthy cooperative children will be enrolled in the study after taking their guardians' informed consent. The study design will be a split mouth design where each patient will be received buffered anaesthetic solution (8.4% sodium bicarbonate will be added to the anaesthetic solution in ratio 1:19) in one side and conventional anaesthetic solution (4% articaine HCL with 1:1000000 epinephrine) in the other side. The pain during injection for each patient in both sides will be then compared using objective and subjective methods. The onset time of the anaesthesia in both sides will also be compared for each patient using Transcutaneous electric nerve stimulator device (TENS) The results will be collected and mentioned. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05473819
Study type Interventional
Source Alexandria University
Contact
Status Active, not recruiting
Phase N/A
Start date May 15, 2022
Completion date September 1, 2022
View Details
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