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Clinical Trial Summary

The objective of this protocol is to conduct longitudinal and prospective studies of liver transplant recipients, using a multimodality approach, akin to that used in kidney transplantation. The primary aim will compare the clinical outcomes of LiverCare post-transplant surveillance in liver transplant with standard of care consisting of liver function tests, DSA measurements, drug level monitoring, and 'for cause' biopsy. The protocol will assess the correlation between clinical events (e.g. rejection, recurrent disease, biliary obstruction), dd-cfDNA levels, gene expression profiling, ability to assess microchimerism, develop predictive analytics, infectious disease diagnoses and finally examine graft histology.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04793360
Study type Observational
Source CareDx
Contact
Status Active, not recruiting
Phase
Start date May 26, 2021
Completion date March 31, 2028

See also
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