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Liver Neoplasms clinical trials

View clinical trials related to Liver Neoplasms.

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NCT ID: NCT05183425 Recruiting - Clinical trials for Explore the Consistency of Drug Sensitivity Between Primary Colorectal Cancer and Liver Metastases

Patient-derived Organoids Predicts the Clinical Efficiency of Colorectal Liver Metastasis

Start date: January 1, 2022
Phase:
Study type: Observational

Accumulating evidence indicates that patient- derived organoids (PDOs) can predict drug responses in the clinic. Metastasis is the main cause of death in colorectal cancer patients, and the treatment of patients with liver metastasis remains poor. Tumor heterogeneity is the cause of treatment failure. In this study, we aim the investigate the consistency of drug sensitivity for the matched primary and metastatic tumor in patients with liver metastasis.

NCT ID: NCT05179824 Recruiting - Breast Cancer Clinical Trials

Tempus Priority Study: A Pan-tumor Observational Study

Start date: October 19, 2020
Phase:
Study type: Observational

Observational study that will be collecting clinical and molecular health information from cancer patients who have received comprehensive genomic profiling and meet the specific eligibility criteria outlined for each cohort with the goal of conducting research to advance cancer care and create a dataset that furthers cancer research.

NCT ID: NCT05178303 Completed - Clinical trials for Cirrhosis of the Liver

Composition for Treating Cirrhosis and Liver Cancer (SB-1121)

SB-1121
Start date: November 30, 2015
Phase: N/A
Study type: Interventional

The composition treats cirrhosis and hepatocellular carcinoma (Hcc) at an early stage. The product is extracted from herbs, including Adenosma glutinosum extract, Eclipta prostrata extract, Phyllanthus urinaria extract, Impatiens balsamina extract, Ascorbic acid, pyridoxine 5-phosphate, L-Arginine hydrochloride, Pregnenolone acetate. These components have participated in repairing and regenerating new liver parenchyma, preventing fibrosis cell generation, preventing liver cancer cell growth at an early stage. The composition supplements precursors which help the body strengthen antibodies and reduce the risk of inflammation, restore physiological and biochemical functions of liver cells after chronic inflammation.

NCT ID: NCT05176860 Completed - Breast Cancer Clinical Trials

Evaluation of Novel Cone-Beam CT for Guidance and Adaptation of Precision Radiotherapy

Start date: December 20, 2022
Phase: N/A
Study type: Interventional

This is a feasibility study investigating the image quality of a new, high-performance cone beam CT (CBCT) used for on-couch imaging during radiotherapy treatments.

NCT ID: NCT05175092 Withdrawn - Clinical trials for Liver Metastasis Colon Cancer

Living Donor Liver Transplantation for CRC Liver Metastases

Start date: November 2023
Phase: N/A
Study type: Interventional

This study will test the safety and efficacy of living donor liver transplant after standard-of-care chemotherapy for participants with non-resectable liver metastases (LM) from colorectal cancer. 25 donor-recipient pairs will be enrolled (50 participants). Donors will be on study for 2 years and recipients will be on study for up to 5 years.

NCT ID: NCT05170282 Recruiting - Hepatoblastoma Clinical Trials

Deep Learning Magnetic Resonance Imaging Radiomics for Diagnostic Value of Hepatic Tumors in Infants

Start date: January 1, 2021
Phase:
Study type: Observational

Hepatic tumors in the perinatal period are associated with significant morbidity and mortality in affected patients. The conventional diagnostic tool, such as alpha-fetoprotein (AFP) shows limited value in diagnosis of infantile hepatic tumors. This retrospective-prospective study is aimed to evaluate the diagnostic efficiency of the deep learning system through analysis of magnetic resonance imaging (MRI) images before initial treatment.

NCT ID: NCT05169177 Recruiting - Liver Neoplasm Clinical Trials

Radio-opaque Contrast Agents for Liver Cancer Targeting With KIM During Radiation Therapy

ROCK-RT
Start date: October 17, 2022
Phase:
Study type: Observational

This observational study will investigate the properties of image files standardly collected during radiation therapy treatment in a cross-section of liver cancer patients who received stereotactic ablative body radiation therapy (SABR) after trans-catheter arterial chemo emobilisation (TACE). Specifically, it will determine whether the radio-opaque contrast agents in the image files can be detected by tumour-tracking software (KIM).

NCT ID: NCT05165446 Active, not recruiting - Clinical trials for NASH - Nonalcoholic Steatohepatitis

Novel MRE Technique to Assess a Risk Factor for Liver Cancer

Start date: January 27, 2022
Phase:
Study type: Observational

The aim of this proposal is to investigate a novel imaging method to identify patients with non-alcoholic steatohepatitis (NASH) who are at risk for hepatocellular carcinoma (HCC).

NCT ID: NCT05164406 Completed - Liver Neoplasms Clinical Trials

Impact of Blood Salvage Therapy on Outcomes After Oncologic Liver Surgery

Start date: January 1, 2018
Phase:
Study type: Observational

A before and after trial comparing the systematic use of blood salvage therapy with leucocyte filter during oncologic liver resections. Recurrence, survival, allogenic transfusion rates and surgical outcomes are compared with a representative historic cohort.

NCT ID: NCT05162898 Not yet recruiting - Clinical trials for Recurrent Hepatocellular Cancer

Radiofrequency Ablation Combined With Toripalimab and Lenvatinib in the Treatment of Short-term Recurrent Hepatocellular Carcinoma.

Start date: January 2022
Phase: N/A
Study type: Interventional

This study is a multi-center, prospective, single-arm, open-design phase II clinical study, mainly to explore the clinical effectiveness and safety of radiofrequency ablation combined with anti-PD-1 antibody toripalimab and lenvatinib in patients with short-term recurrence of hepatocellular carcinoma.