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Stereotactic Body Radiation Therapy vs. Microwave Ablation for Colorectal Cancer Patients With Metastatic Disease in the Liver

Liver Metastases Clinical Trial

Official title:
Stereotactic Body Radiation Therapy vs. Microwave Ablation for Colorectal Cancer Patients With Metastatic Disease in the Liver - a Randomized Phase II Trail

Clinical Trial Summary

This study is a randomized phase II trial between microwave ablation (MWA) and stereotactic body radiotherapy (SBRT) - two standard treatment modalities for colorectal patients with metastatic disease in the liver. Primary endpoint is freedom form local lesion progression.

Clinical Trial Description

Colorectal cancer patients with 1-3 liver metastases (diameter ≤4.0 cm) found unsuitable for resection are randomized 1:1 to either MWA or SBRT. Chemotherapy is allowed. Curative treatment of extrahepatic disease must be initiated in patients with lung metastases and/or primary tumors. Patients will be analyzed according to the intention-to-treat principle. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03654131
Study type Interventional
Source Rigshospitalet, Denmark
Contact
Status Recruiting
Phase Phase 2
Start date July 25, 2018
Completion date July 25, 2026
View Details
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