Liver Diseases Clinical Trial
Official title:
Randomised Controlled Study Comparing Use of Popofol Plus Fentanyl Versus Midazolam Plus Fentanyl as Sedation in Diagnostic Endoscopy in Patients With Advanced Liver Disease.
Gastrointestinal endoscopy is a frequent procedure in the patients with advanced liver
disease. It requires variable degree of sedation ranging from minimal sedation to general
anesthesia aiming for relieving pain, anxiety, and bad memories of the procedure.
In conscious sedation, patients are able to make purposeful responses to auditory and
tactile clues, with maintenance of ventilatory and circulatory stability. while, in deep
sedation, patients respond only to painful stimuli, and airway support is frequently
required. At the level of general anesthesia, patients are unresponsive, and airway support
is mandatory.
The aim of this study is to compare use of propofol or midazolam as sedative for patients with advanced liver disease presented for gastrointestinal endoscopy. ;
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