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NCT03868397 Clinical Trial

Preoperative Portal and Splanchnic Flow Measurement Using MRI

Liver Cirrhoses Clinical Trial

Official title:
Preoperative Portal and Splanchnic Flow Measurement in Living Donor Liver Transplantation Recipient With Spontaneous Portosystemic Shunt at MRI: Preliminary Study

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT03868397
Other study ID # SNUH-2017-1262
Secondary ID
Status Active, not recruiting
Phase N/A
First received
Last updated
Start date March 7, 2019
Est. completion date December 31, 2023

Study information
Verified date April 2023
Source Seoul National University Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

This study aims to assess the alteration of portal and splanchnic flow using MRI after liver transplantation in patients with splenomegaly or splenic varix.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 12
Est. completion date December 31, 2023
Est. primary completion date July 12, 2019
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - older than 18 years - And signed informed consent - And planned either a) liver transplantation as a recipient; or b) liver transplantation as a donor Exclusion Criteria: - any absolute/relative contraindication of contrast-enhanced MRI

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• Liver MRI
Liver MRI including 4D flow sequence is performed twice in liver transplantation recipients, before and 1 month-after transplantation. In donor candidates, liver MRI including 4D flow sequence is performed twice in 1-3 weeks to assess repeatability of the technique.

Locations
Country Name City State
Korea, Republic of Seoul National University Hospital Seoul

Sponsors (1)
Lead Sponsor Collaborator
Seoul National University Hospital

Country where clinical trial is conducted

Korea, Republic of, 

Outcome
Type Measure Description Time frame Safety issue
Primary Portal flow portal flow measured with MRI (4D flow sequence) in a month after 2nd MRI
Secondary SMV flow superior mesenteric vein (SMV) flow measured with MRI (4D flow sequence) in a month after 2nd MRI
Secondary Splenic vein flow splenic vein flow measured with MRI (4D flow sequence) in a month after 2nd MRI
Secondary splenic varix flow splenic varix flow measured with MRI (4D flow sequence) only in liver recipients in a month after 2nd MRI
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