Clinical Trials Logo

Clinical Trial Summary

Machine perfusion technology is nearing the point of rescuing discarded liver grafts in the hope of proving them to be or improving them to the point of being transplantable. However, there are no validated metrics to determine transplantability after machine perfusion. This study involves collecting biopsies from transplanted livers before and after implantation to correlate metabolite and gene expression with post-transplant function. This data will help develop a viability index for machine perfused livers.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03694691
Study type Interventional
Source Massachusetts General Hospital
Contact Heidi Yeh, MD
Phone 617-726-3664
Email hyeh@mgh.harvard.edu
Status Recruiting
Phase N/A
Start date October 1, 2018
Completion date June 1, 2025

See also
  Status Clinical Trial Phase
Terminated NCT03219372 - Pravastatin Intervention to Delay Hepatocellular Carcinoma Recurrence Phase 2
Recruiting NCT03624517 - Comparison of 24-hours Versus 72-hours of Octreotide Infusion in Preventing Early Rebleed From Esophageal Varices Phase 4
Recruiting NCT04057287 - Risk Factors of Liver Fibrosis Among First Degree Relatives of Patients With NASH Related Cirrhosis (NRC)
Recruiting NCT04089878 - "To Study the Impact of Balloon-occluded Retrograde Transvenous Obliteration (BRTO)/Plug Assisted Retrograde Transvenous Obliteration (PARTO) Mediated Portal Flow Modulation in Reduction of Ammonia and Improvement in Organ Volume and Functionality in Patients of Cirrhosis With LR Shunt N/A
Completed NCT04212286 - Comparing the Diagnostic Efficiencies of CEUS and EOB-MRI in Patients With High Risk of HCC N/A
Completed NCT04474743 - Malnutrition in Chronic Gastrointestinal Diseases, Cross-sectional Study
Terminated NCT04072601 - Statins for Prevention of Disease Progression and Hospitalization in Liver Cirrhosis Phase 4
Terminated NCT03878563 - Alterations in Intestinal Mucosal Barrier Visualized by Confocal Laser Endomicroscopy in Liver Cirrhosis: a Pilot Trial (AMBIC)
Terminated NCT04160039 - Early Cycle Ergometry for Critically-Ill Liver Failure Patients in a Transplant Intensive Care Unit N/A
Recruiting NCT04191369 - EGD vs EUS in Diagnosing Portal Hypertension in Cirrhotic Patients. N/A
Completed NCT03083925 - Viatorr CX Case-control Study for Complications of Portal Hypertension
Not yet recruiting NCT03855709 - Antibiotic-resistant Bacterial Infection of Hepatic Patients
Recruiting NCT02484573 - Evaluation of Intestinal Permeability in Cirrhotic Patients Before and After Treatment With Non-selective Beta Blocker (Propranolol) N/A
Recruiting NCT04357600 - Umbilical Cord Mesenchymal Stem Cell for Liver Cirrhosis Patient Caused by Hepatitis B Phase 1/Phase 2
Completed NCT03156426 - Prognostic Biomarkers For Acute Kidney Injury In Liver Cirrhosis
Active, not recruiting NCT03868397 - Preoperative Portal and Splanchnic Flow Measurement Using MRI N/A
Terminated NCT03650660 - Concordance Between Echocardiographic Assessment Performed in the Initial Phase of Decompensated Cirrhosis With Edema and Ascites by an Expert Intensive Care Physician and a Non-expert Gastroenterologist
Completed NCT03871894 - Indirect Calorimeter Based Study in Patients With Liver Cirrhosis N/A
Completed NCT03283176 - Hematologic Profile, Vit. B12 and Folic Acid in Cirrhotics Received Sofosbuvir and Daclatasvir With or Without Ribavirin
Recruiting NCT03172273 - Early Use of TIPS With Polytetrafluoroethylene(PTFE) Covered Stents in Cirrhotic Patients With Refractory Ascites N/A