Liver Cancer Clinical Trial
Official title:
Follow-up Yttrium-90 Internal Pair Production PET/CT Imaging in Patients With Primary or Metastatic Liver Tumors as Compared With Brehmsstrahlung Imaging: A Prospective Case Series
This is a prospective non-blinded case series involving the acquisition of a pair production
PET/CT as soon as possible after an already performed Y-90 Sirspheres treatment of hepatic
malignancy. It will be performed in addition to the standard Brehmsstrahlung SPECT scan. The
sequence of the two scans in each case (PET/CT vs SPECT) will be determined by availability
of the scanners at the time. However, it is intended that both be acquired on the day of the
Y-90 treatment.
The length of subject participation will be one year.
The measures used will be mostly qualitative in nature, and will include:
- Correlation with expected vs. achieved tumor coverage by the treatment
- Correlation between treatment distribution depicted by Brehmsstrahlung scans vs. the
Internal Pair Production PET/CT scans, to.
- Detection of non-target embolization, where applicable, and qualitative comparison
between the two modalities as to the conspicuity of the abnormality
Qualitative methods will be used by the analysis of the obtained PET/CT images and comparing
them to the Brehmsstrahlung SPECT images as previously described.
n/a
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