Peroneus Longus Graft :Effect in Foot and Ankle Function

Ligament Injury Clinical Trial

Official title:

Peroneus Longus Autograft Use in Knee, Shoulder, Elbow Ligaments Reconstruction Surgery : Effect On Ankle And Foot Function

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT05991557
• Other study ID #: peroneus longus graft
• Status: Not yet recruiting
• Phase: N/A
• Start date: September 1, 2023
• Est. completion date: December 2025

Study information

• Verified date: August 2023
• Source: Assiut University
• Contact: mahmoud sabra ahmed, resident doctor
• Phone: +0201006721501
• Email: ahmedsabra310[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to report the ankle and foot functions via American orthopedic foot and ankle society score (AOFAS), peronei muscle testing ,handheld dynamometer and radiological outcomes after harvesting autogenous peroneus longus tendons for ligaments reconstruction.

Description:

Using a Peroneus longus tendon (PLT) as an autograft is a common procedure and has been used previously for deltoid ligament reconstruction in flatfoot deformity correction . Recently, (PLT) is gaining popularity as a graft option in primary anterior cruciate ligament (ACL) reconstruction surgeries with biomechanical studies showing tensile strength and clinical outcomes comparable to quadrupled hamstring grafts.

In addition to using PLT for isolated (ACL), it is also used in posterior cruciate ligament (PCL) reconstruction, medial collateral ligament reconstruction, posterolateral corner reconstruction of the knee, or knee multiple ligament injuries . The partial-thickness of the tendon has been used variably in knee ligament surgery..

Being a powerful muscle in plantar flexion and eversion of the foot, there might be associated ankle functional impairment. To the authors knowledge, there is a gap in science evaluating donor site morbidity. The aim of this study is to report the clinical and functional outcome of the donor site for better explanation of the cons and pros of using PLT as a graft in joint ligamentous injury .

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 54
• Est. completion date: December 2025
• Est. primary completion date: September 2025
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 50 Years

Eligibility

Inclusion Criteria:

1. clinical and radiological diaginsis of joint ligament injury and needs to ligament reconstruction .

2. people with asymptomatic ankle and foot pre and post injury

Exclusion Criteria:

1. Associated ankle and/or foot fractures.

2. Associated hip or pelvic fractures

3. Abnormal ankle function pre-injury.

4. Contralateral limb fractures

5. Traumatic brain injury (TBI) that limits their ability to participate in their post-operative care;

6. Presence of neurological condition that result in spasticity or any abnormal lower limb muscles tone.

7. Any condition that would preclude the ability to comply with post-operative guidelines.

Related Conditions & MeSH terms

• Ligament Injury

Intervention

Procedure:
• peroneus longus autograft
Peroneus longus tendon graft will be harvested with a longitudinal skin incision at 2 to 3 cm (2 finger-breadths) above and 1 cm (1 finger-breadth) behind the lateral malleolus, followed by superficial fascia incision in line with skin incision followed by incision of the tendon sheath proximal to the retinaculum. The peroneus longus and peroneus brevis tendons will be then identified. The tendon division location marked at 2 to 3 cm above the level of the lateral malleolus.The peroneus longus tendon will be exposed on its posterolateral surface through the incision after carefully incising the fascia

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	peronei muscle strength testing using handheld dynamometer	power of plantar flexion and eversion of foot and ankle	preoperative, three months postoperative and six months postoperative

External Links

•   -Setyawan R, Soekarno NR, Asikin AIZ, Rhatomy S (2019) Posterior cruciate ligament reconstruction with peroneus longus tendon graft: 2-years follow-up. Ann Med Surg 43:38-43
•   2- Rudy ME, Phatama KY (2017) Tensile strength comparison between peroneus longus and hamstring tendons: a biomechanical study. Int J Surg Open 9:41-44
•   3- Rhatomy S, Asikin AIZ, Wardani AE et al (2019) Peroneus longus autograft can be recommended as a superior graft to hamstring tendon in single-bundle ACL reconstruction. Knee Surg, Sport Traumatol Arthrosc.
•   Shi F-D, Hess DE, Zuo J-Z et al (2019) Peroneus longus tendon autograft is a safe and effective alternative for anterior cruciate ligament reconstruction. J Knee Surg 32:804-811