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Leukomalacia, Periventricular clinical trials

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NCT ID: NCT00369005 Completed - Anemia Clinical Trials

Liberal Versus Restrictive Transfusion Guidelines for Preterm Infants

Start date: December 1992
Phase: N/A
Study type: Interventional

The purpose of this study was to determine whether restrictive guidelines for red blood cell (RBC) transfusions for preterm infants can reduce the number of transfusions without adverse consequences.

NCT ID: NCT00120588 Completed - Preterm Birth Clinical Trials

Neuroprotection by Magnesium Sulfate Given to Women at Risk of Very Preterm Birth

Start date: July 1997
Phase: Phase 4
Study type: Interventional

Magnesium is neuroprotective in neonatal animal models of acquired hypoxic-ischemic and/or inflammatory cerebral lesions. It is associated with a significant reduction of perinatal death and cerebral palsy in some observational studies. The objective of the study is to assess if prenatal magnesium sulfate given to women at risk of preterm birth before 33 week's gestation is neuroprotective.

NCT ID: NCT00014989 Completed - Cerebral Palsy Clinical Trials

Beneficial Effects of Antenatal Magnesium Sulfate (BEAM Trial)

BEAM
Start date: December 1997
Phase: Phase 3
Study type: Interventional

As many more premature infants survive, the numbers of these infants with health problems increases. The rate of cerebral palsy (CP) in extremely premature infants is approximately 20%. Magnesium sulfate, the most commonly used drug in the US to stop premature labor, may prevent CP. This trial tests whether magnesium sulfate given to a woman in labor with a premature fetus (24 to 31 weeks out of 40) will reduce the rate of death or moderate to severe CP in the children at 2 years. The children receive ultrasounds of their brains as infants and attend three follow-up visits over two years to assess their health and development.