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Clinical Trial Summary

The purpose of this study is to evaluate the safety and efficiency of high dose allogeneic mismatched hematopoietic stem cells infusions after normal chemotherapy in patients with relapsed/refractory acute myeloid leukemia(AML).


Clinical Trial Description

The relapsed/refractory AML patients will receive IA/DA/MA(I,Idamycin,D,Daunorubicin,M,Mitoxantrone,A,cytosine arabinoside) chemotherapy followed by infusion of high dose allogeneic mismatched hematopoietic stem cells.

no graft-versus-host disease (GVHD) prevention will be conducted before transplantation. Cytokine storm,GVHD snd donor graft will be detected post-transplantation. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03080922
Study type Interventional
Source The Affiliated Hospital of the Chinese Academy of Military Medical Sciences
Contact HUISHENG AI
Email HUISHNGAI@163.COM
Status Recruiting
Phase Phase 1/Phase 2
Start date March 2016
Completion date March 2019

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