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Leukemia, Myeloid clinical trials

View clinical trials related to Leukemia, Myeloid.

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NCT ID: NCT05611216 Completed - Clinical trials for Chronic Myeloid Leukemia

Clinical Outcomes of 3L+ Therapies Among Patients With Chronic Myeloid Leukemia and Those With T315I Mutation

Start date: December 1, 2020
Phase:
Study type: Observational

The study was a retrospective, non-interventional patient chart review and used a panel of oncologists/hematologists from the US to collect real-world clinical outcomes of patients with CML-CP in 3L+ and those with the T315I mutation.

NCT ID: NCT05563207 Completed - Clinical trials for Acute Myeloid Leukemia

Application of Health Education Path of Traditional Chinese Medicine Nursin

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

To explore the effect of traditional Chinese medicine (TCM) health education standard path on the treatment of patients with acute myeloid leukemia (AML). A total of 60 patients with acute myeloid leukemia in Shijiazhuang Ping An Hospital were selected and divided into control group (n=30) and observation group (n=30) according to the time of admission. Both groups received the same chemotherapy, the control group received routine nursing, and the observation group received TCM health education standard path intervention. The scores of Self-rating Anxiety Scale (SAS), Self-rating Depression Scale (SDS), Spitzer Quality of Life Index (QLI), awareness of TCM health education standard path content and nursing satisfaction were compared between the two groups.

NCT ID: NCT05541224 Completed - Clinical trials for Acute Myeloid Leukemia

A Retrospective Epidemiologic Registry to Gain Insight Into the Characteristics and Prognosis of AML Patients According to the Routinely Used Genetic and Biologic Markers

Start date: November 1, 2019
Phase:
Study type: Observational

This is a retrospective, translational, epidemiologic, multicenter, non-interventional study (No EPA study) to provide insights into disease epidemiology, disease biology, treatment regimens, and clinical outcomes of patients with acute myeloblastic leukemia (AML) in routine clinical practice according to their molecular markers. The primary objective of the study is to describe the use of the main molecular markers (FLT3 and NPM1) in the real-life according of the type of AML, treating institution, patients' characteristics, and disease status.

NCT ID: NCT05518357 Completed - Clinical trials for Relapsed/Refractory Acute Myeloid Leukemia

LILRB4 STAR-T Cells in the Treatment of Relapsed/Refractory Acute Myeloid Leukemia

Start date: June 24, 2022
Phase: Phase 1
Study type: Interventional

This is a single-center, single-arm, open-label phase I clinical study to determine the safety and efficacy of LILRB4 STAR-T cells in relapsed/refractory acute myeloid leukemia subjects.

NCT ID: NCT05488613 Completed - Clinical trials for Acute Myeloid Leukemia (AML)

Healthcare Resource Utilization in Adults Diagnosed With Acute Myeloid Leukemia (AML)

Start date: September 24, 2020
Phase:
Study type: Observational

This was a non-interventional, retrospective registry study, utilizing electronic health record (EHR) data collected in the hospital district of Helsinki and Uusimaa (HUS). Real-world health care resource utilization (HCRU) of AML patients was characterized.

NCT ID: NCT05476562 Completed - Clinical trials for Chronic Myeloid Leukemia

Study Conducted Among Patients With CML

Start date: March 8, 2021
Phase:
Study type: Observational

Retrospective, non-interventional observational cohort study conducted among patients with CML.

NCT ID: NCT05456048 Completed - Clinical trials for Refractory Acute Myeloid Leukemia

Influence of Molecular Abnormalities on Response of VAH vs. VEN+HMA in RR-AML

Start date: December 3, 2018
Phase:
Study type: Observational

The aim of this study is to reveal the influence of gene mutations on the treatment response of the regimen of HHT combined with Venetoclax plus AZA versus venetoclax plus HMA in the salvage therapy of RR-AML.

NCT ID: NCT05433532 Completed - Clinical trials for Acute Myeloid Leukemia

Study of Azacitidine,Venetoclax,and Flumatinib in Newly Diagnosed Ph-positive Acute Leukemia and CML-AP/BP Patients

Start date: May 1, 2022
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of azacitidine,venetoclax,and flumatinib in newly diagnosed Philadelphia chromosome-positive acute leukemia and accelerated phase or blast phase chronic myeloid leukemia patients.

NCT ID: NCT05421091 Completed - Clinical trials for Chronic Myeloid Leukemia

Special Drug Use-results Surveillance of Scemblix Tablets

Start date: July 4, 2022
Phase:
Study type: Observational

Uncontrolled, central registration system, all-case, multicenter, special drug use-results surveillance.

NCT ID: NCT05387330 Completed - Clinical trials for Chronic Myeloid Leukemia

Dynamic Changes in the Levels of sCD62L and SPARC in Chronic Myeloid Leukemia Patients During Imatinib Treatment

Start date: April 1, 2018
Phase:
Study type: Observational

This study aims to monitor the levels of soluble L-selectin (sCD62L) and secreted protein acidic rich in cysteine (SPARC) in chronic phase chronic myeloid leukemia (CP-CML) patients at baseline and after three and six months of imatinib therapy and evaluated the effect of imatinib on their levels and correlated their levels to clinical and laboratory parameters.