Infection Clinical Trial
Official title:
Observational and Comparative Study on the Immune Response of Patients With Chronic, Staphylococcus Aureus-infected Wounds (Localized Infections Versus Bacteremia)
The primary objective of this study is to detect differences in anti-S. aureus antibody assays (IgM, IgA, IgG and its subclasses) between (1) a group of patients with bacteremia due to a chronic wound (cases) and (2) a group of patients with localized chronic wound infections (control).
Secondary objectives include:
- To propose a diagnostic marker of bacteraemia based on the detection of anti-S. aureus
by xMAP technology
- To evaluate the kinetics of the humoral immune response to S. aureus in patients with
bacteraemia
- To evaluate the virulence of S. aureus isolated from chronic, infected wounds
- To enrich the Nîmes University Hospital biobank
- To evaluate the prevalence of different antibodies within each group
;
Observational Model: Case Control, Time Perspective: Prospective
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