Clinical Trials Logo
  1. Home
  2. Left Ventricular Assist Device
  3. NCT03217331

CRD-102 for Right Heart Failure in Patients With Left Ventricular Assist Devices

Right Heart Failure Clinical Trial

Official title:
CRD-102 for Right Heart Failure in Patients With Left Ventricular Assist Devices

Clinical Trial Summary

This is a Phase 1b/IIa, single centre, non-randomised open-label uncontrolled study to assess safety, effect and PK of oral CRD-102 in patients with RHF associated with the presence of an LVAD.

Clinical Trial Description

The study will be conducted over a 40 day time period inclusive of screening and follow up time periods. Eligible subjects will receive oral CRD-102 for 14 days. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03217331
Study type Interventional
Source Cardiora Pty. Ltd.
Contact
Status Completed
Phase Phase 1/Phase 2
Start date March 6, 2018
Completion date May 30, 2019
View Details
See also
  Status Clinical Trial Phase
Completed NCT05948332 - Definition and Management of Right Ventricular Injury in Adult Patients Receiving Extracorporeal Membrane Oxygenation
Not yet recruiting NCT06002321 - Right Ventricular Dysfunction in Chronic Heart Failure
Not yet recruiting NCT06039176 - Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future
Completed NCT03438825 - PRediction of Early PostoperAtive Right vEntricular Failure in Mitral Valve Replacement/Repair Patients
Recruiting NCT05179616 - Pforzheim Tricuspid Valve Registry - Outcomes of Percutaneous Tricuspid Valve Repair
Completed NCT02644616 - The Safety and Efficacy of Tolvaptan for Patients With Tricuspid Regurgitation and Right Heart Failure After Left Heart Valves Replacement Phase 4
Completed NCT03656263 - The Clinical Significance of Portal Hypertension After Cardiac Surgery: a Multicenter Prospective Observational Study
Recruiting NCT01777607 - The Use of Impella RP Support System in Patients With Right Heart Failure N/A
Completed NCT03554291 - Repurposing a Histamine Antagonist to Benefit Patients With Pulmonary Hypertension Phase 2
Not yet recruiting NCT00834145 - Effect of Normatec Pump for Relief of Leg Edema in Patients With Right Heart Failure N/A
Recruiting NCT03552679 - Serial Multiparametric Evaluation of Right Ventricular Function After Left Ventricular Assist Device Implantation
Recruiting NCT03202641 - Open Lung Strategy, Gas Distribution and Right Heart Function in ARDS Patients N/A
Not yet recruiting NCT05450328 - Inhaled Milrinone and Epoprostenol for the Prevention of Difficult Cardiac Pulmonary Bypass Separation Phase 2
Not yet recruiting NCT04188756 - RV Systolic and Diastolic Function and Contractile Reserve Under Acute Exercise and in Response to Chronic Exercise-based Rehabilitation N/A
Completed NCT01757522 - Detection of Right Ventricular Dysfunction by 2D Strain During Acute Respiratory Distress Syndrom (ARDS)
Withdrawn NCT00811486 - Body Volume Regulation in Pulmonary Arterial Hypertension With Right Ventricular Failure N/A
Completed NCT05366400 - Relationship Between Right Atrial Volume Index, Functional Capacity and Inflammatory Biomarkers in Patients With COPD.
Terminated NCT03073629 - Assessing Outcomes in ED Patients With RV Failure N/A
Active, not recruiting NCT06023134 - Clinical Characteristics and Outcomes of Patients With Pulmonary Hypertension Associated Right Heart Failure
Recruiting NCT06053580 - Repurposing Valsartan May Protect Against Pulmonary Hypertension Phase 2