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Pulse Wave Analysis in Advanced Heart Failure — PWA-HF  

Heart Failure Clinical Trial

Official title:
Pulse Wave Analysis in Advanced Heart Failure Patients Before and After Ventricular Assist Device

Clinical Trial Summary

A comparison of pulse wave characteristics, as measured by peripheral tonometry, in pre and post Left Ventricular Assist Device (LVAD) patients.

Clinical Trial Description

Pulse waveforms, especially central pressure waveforms, are predictive of cardiovascular events. Peripheral waveforms have been correlated to central waveforms. Peripheral waveforms can be easily measured through applanation tonometry. In this study the investigators hypothesize: 1. That previously established peripheral tonometry techniques would apply to patients with advanced heart failure, including continuous flow LVADs and facilitate serial evaluation of central hemodynamics without invasive monitoring. 2. That temporary changes in LVAD speed will be evident in frequency spectrum analysis of peripheral, non-invasive waveforms. 3. That clinical events involving LVAD will have characteristic frequency spectra. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01642927
Study type Observational
Source University of Minnesota
Contact
Status Withdrawn
Phase
Start date February 2012
Completion date December 2016
View Details
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