Left Atrial Appendage Closure Clinical Trial
Official title:
Intracardiac Versus Transesophageal Echocardiographic Guidance for Left Atrial Appendage Occlusion
This single-center, prospective, randomized study will evaluate the safety and feasibility of Intracardiac echocardiography (ICE)-guided Left atrial appendage closure (LAAC) when compared to the traditional Transesophageal echocardiography (TEE) approach.
The primary objective of this study is to assess the efficacy and safety of using Intracardiac echocardiography (ICE) to guide implantation of percutaneous left atrial appendage closure (LAAC) devices. Primary endpoints include procedural success following implantation of the left atrial appendage occlusion (LAAO) device. Procedural success specifies that the device should be implanted in the correct position without device related complications and no peri-device leaks >5 mm on color doppler. Secondary end points include periprocedural complications (such as pericardial effusion/tamponade, stroke, death, vascular complications, and device embolization), procedural characteristics (total duration, fluoroscopy time, contrast volume, Length of hospital stay), cost of hospitalization, in-hospital patient satisfaction, and clinical alterations at 45-day follow-up. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Not yet recruiting |
NCT06293430 -
Registry on Luma Vision's VERAFEYE System (ENLIgHT)
|
||
| Recruiting |
NCT03568890 -
Short-Term Anticoagulation Versus Antiplatelet Therapy for Preventing Device Thrombosis Following Left Atrial Appendage Closure
|
Phase 4 | |
| Recruiting |
NCT03014557 -
China REgistry of WATCHMAN
|
N/A | |
| Recruiting |
NCT03409159 -
Austrian Left Atrial Appendage Closure Registry
|
||
| Recruiting |
NCT03088072 -
A Pilot Study of Edoxaban in Patients With Non-Valvular Atrial Fibrillation and Left Atrial Appendage Closure
|
Phase 4 | |
| Completed |
NCT03040622 -
The Evaluation of Thrombogenicity in Patients Undergoing WATCHMAN Left Atrial Appendage Closure Trial
|
||
| Withdrawn |
NCT02309268 -
Atrial Appendage Closure Prospective Observational Study
|
N/A | |
| Active, not recruiting |
NCT03399851 -
Comparison of Amplatzer Amulet and Watchman Device in Patients Undergoing Left Atrial Appendage Closure. (SWISS-APERO)
|
N/A | |
| Recruiting |
NCT05743322 -
The Usefulness of Biatrial 3D Printing to Plan Transseptal Puncture for the Left Atrial Appendage Closure
|
N/A | |
| Not yet recruiting |
NCT05931835 -
Feasibility Study on the VERAFEYE System
|
N/A | |
| Completed |
NCT03147391 -
Left Atrial Appendage Closure With the LAmbre
|
N/A |