Effects of Oxytocin on Reinforcement Learning

Learning Disabilities Clinical Trial

Official title: The Effects of Intranasal Oxytocin on Reward Sensitivity and Performance Monitoring During Reinforcement Learning: an ERP Study

Status Recruiting

Clinical Trial Summary

The main aim of the study is to investigate whether intranasal oxytocin (24IU) influences reward sensitivity and performance monitoring during reinforcement learning.

Clinical Trial Description

A double-blind, within-subject, placebo-controlled pharmacological EEG design will be employed. A total of 35 healthy male subjects will be recruited which will receive either intranasal placebo or oxytocin (24IU) on two separate study days (order counter-balanced, washout period at least 2 weeks). 45 minutes after treatment subjects will undergo a probabilistic feedback reinforcement learning paradigm with concurrent EEG acquisition. During the paradigm subjects will learn the reward probabilities of two different visual stimuli from probabilistic feedback provided by social stimuli (positive, negative emoticon). The paradigm includes an initial acquisition phase and a subsequent test phase. ;

Related Conditions & MeSH terms

• Learning Disabilities
• Learning Disorders

• NCT number: NCT03846271
• Study type: Interventional
• Source: University of Electronic Science and Technology of China
• Contact: Zhuang Qian, MD
• Phone: 13086663679
• Email: zq19910362@126.com
• Status: Recruiting
• Phase: N/A
• Start date: December 4, 2018
• Completion date: July 31, 2019