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Markers of Platelet Activation foR Identification of Late Onset Sepsis in Preterm Infants — PARENT  

Late-Onset Neonatal Sepsis Clinical Trial

Official title:
Markers of Platelet Activation foR Identification of Late Onset Sepsis in Preterm Infants

Clinical Trial Summary

The PARENT study will examine platelet and endothelial associated proteins in preterm infants being investigated for late onset sepsis (LOS) to see if infants with fulminant sepsis can be prospectively identified using these markers

Clinical Trial Description

Infants who are less than 34 weeks corrected gestational age at time of birth will be enrolled prior to any late onset sepsis investigations. At point of clinical concern for the development of late onset sepsis a 0.5-1.3ml sodium citrate sample will be taken. A targeted proteomic analysis using mass spectroscopy and flow cytometry will be performed and compared with the clinical diagnosis of the infant to examine if this can be used prospectively to identify infants with late onset sepsis ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05530330
Study type Observational
Source University College Dublin
Contact Daniel O'Reilly
Phone +353876610771
Email daniel.oreilly2@ucdconnect.ie
Status Recruiting
Phase
Start date September 2, 2022
Completion date July 14, 2025
View Details
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