Late-Onset Neonatal Sepsis Clinical Trial
Official title:
Intestinal Microbiome Strain-level Stability in NEC/ or LOS Patients
Study around very-low birthweight preterm infants at high risk of developing necrotizing enterocolitis (NEC) or late-onset sepsis (LOS). Collection of stool and other biological samples to assess the strain-level stability of gastrointestinal microbiota in these preterm infants who may or may not develop NEC/LOS.
This study aims to collect biological samples (stool, stomach fluid, and blood) from preterm infants at risk of developing NEC or LOS; as well as environmental samples from infants' hospital surroundings (swabs, air), nutritional intake (formula, breastmilk) and samples from their family members (faeces, vaginal swab). The main focus of the study is to assess strain-level stability of gastrointestinal microbiota in these infants and potentially assess the source of disease-causing microbiota species/strains. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05530330 -
Markers of Platelet Activation foR Identification of Late Onset Sepsis in Preterm Infants
|
||
| Not yet recruiting |
NCT06199102 -
The High Initial Dose of Monitored Vitamin D Supplementation in Preterm Infants.
|
N/A | |
| Recruiting |
NCT04717037 -
Olive Oil Massage Effect for Reduction of Preterm Sepsis (OMEPS)
|
Phase 2/Phase 3 | |
| Completed |
NCT03299751 -
Evaluation of bioMarkErs to Reduce Antibiotics Use in hospitalizeD nEonates
|
N/A | |
| Not yet recruiting |
NCT06118801 -
The Effect of Probiotics Added to the Mother's Diet on Preterm Babies
|
N/A | |
| Recruiting |
NCT04842786 -
Topical Coconut Oil Application and Incidence of Sepsis in Neonates
|
N/A | |
| Completed |
NCT03822104 -
Bovine Colostrum as a Human Milk Fortifier for Preterm Infants
|
N/A | |
| Completed |
NCT04424667 -
Clinical Impact of Donor Milk Pasteurized by HTST Treatment in Preterm Infants
|
N/A | |
| Recruiting |
NCT05981079 -
Model-based Dose Versus Empirical Dose of Piperacillin/Tazobactam in Preterm Neonates With Late-onset Sepsis.
|
Phase 4 | |
| Recruiting |
NCT05991648 -
Effect of Kangaroo Care on Heart Rate Variability in Late-onset Neonatal Sepsis
|
N/A | |
| Completed |
NCT03085277 -
Bovine Colostrum for Preterm Newborns
|
N/A | |
| Recruiting |
NCT05347238 -
Dopamine vs. Norepinephrine for Hypotension in Very Preterm Infants With Late-onset Sepsis
|
||
| Recruiting |
NCT03997266 -
NICU Antibiotics and Outcomes Trial
|
Phase 4 | |
| Completed |
NCT03633500 -
Effectiveness of Oral Immunotherapy Among Preterm Babies
|
N/A |