Larynx Clinical Trial
Official title:
Descriptive In Vivo Study of Evaluating the Innervation of The Human Cricopharyngeal Muscle By The Recurrent Laryngeal Nerve and External Branch of The Superior Laryngeal Nerve
The investigators hypothesized that, external branch of the superior laryngeal nerve (EBSLN) and/or recurrent laryngeal nerve (RLN) contribute to the motor function of the human cricopharyngeal muscle (CP). The investigators aimed to assess the contribution of the laryngeal nerves (EBSLN and RLN) to the motor activity of the cricopharyngeal muscle, during thyroidectomy with intraoperative neuromonitoring (IONM).
This study group consisted of a consecutive patients undergoing thyroid surgery with
intraoperative neuromonitoring (NIM 3.0 Nerve Monitoring Systeme (Medtronic Xomed,
Jacksonville, FL, USA) ) for various diseases. In all patients, each side of the neck
operated was considered as a separate entity in our study.
EMG recordings were accomplished with a pair of needle electrodes inserted into the CP and
mid-portion of the CT muscle that is located on the superior side of the RLN, which were
plugged into the third and fourth channels of interface-connector box, respectively, at the
end of the thyroidectomy or lobectomy. The investigators evaluated the innervation pattern
of the CT muscle in an other study. Therefore the EBSLN is the main supplier of the CT
muscle, the EMG findings of the CT muscle were used to confirm it, in this study.
EBSLN, pharyngeal plexus (PP), RLN and vagus nerve were stimulated with a monopolar
stimulator probe at 1 mA. While stimulating these nerves, the ipsilateral CP muscle was
visually observed for possible contractions and electromyographic recordings were obtained
with the 4-channel NIM 3.0 Nerve Monitoring System.
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Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Basic Science
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