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CLE During Exercise Testing in Asthma — CLEtesting  

Larynx Clinical Trial

Official title:
Continuous Laryngoscopy During Exercise Testing in Patients With Asthma

Clinical Trial Summary

The purpose is to assess visualize the level of laryngeal obstruction and vocal cord dysfunction and to obtain more information on causes for dyspnea in asthma and severe asthma and to assess safety of CLE in patients with asthma and with severe asthma. Patients are examined if symptomatic during exercise.

Clinical Trial Description

- Questionnaires to assess breathlessness before the test. - CLE on ergometer bicycle using any laryngoscopy setup - Ergometry with spirometry tests with ECG, oxygen saturation, blood pressure, inspiratory and expiratory flow volume curves, bronchodilator after the exercise test - Work load of 40W with 3 minutes intervals and increase by 40W in women. In men, work load of 50W with 3 minutes intervals and increase by 50W starting from 50W. In elderly and more severely disease work load of 30W with 3 minutes intervals and increase by 30W. - Recording of dyspnoea, leg fatigue and chest discomfort - Assessment of asthma by asthma control test, spirometry, exhaled NO measurements. - Severe asthma group: physician-diagnosed asthma, moderate-high dose inhaled glucorticoid steroids and a second controller drug, exacerbations and per oral glucocorticoid steroid courses at least 2 in the past 12 months and/or 50% of the past 12 months on per oral glucocorticoidsteroids ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04168671
Study type Interventional
Source Helsinki University Central Hospital
Contact
Status Withdrawn
Phase N/A
Start date March 1, 2019
Completion date December 31, 2021
View Details
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