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Laparoscopy clinical trials

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NCT ID: NCT03815344 Completed - Laparoscopy Clinical Trials

Combined Vaginal Misoprostol and Perivascular Vasopressin

Start date: April 26, 2017
Phase: Phase 4
Study type: Interventional

Injection of Vasopressin into the uterine tissue surrounding fibroids constricts blood vessels, and has been found to be beneficial by decreasing blood flow to fibroids, and thereby resulting in less bleeding with removal. Additionally, Misoprostol has been looked at as an additional method to decrease operative blood loss given its ability to increase uterine muscle tone, which therefore constricts the amount of blood flow to the uterus.

NCT ID: NCT03792932 Recruiting - Pancreatic Cancer Clinical Trials

Laparoscopic vs Open Pancreatectomy for Body and Tail Pancreatic Cancer

Start date: February 2, 2019
Phase: N/A
Study type: Interventional

Open distal pancreatectomy (ODP) has been commonly employed for the treatment of a variety of cancers in body and tail of pancreas. Although many general surgical procedures have been increasingly performed laparoscopically or with laparoscopic assistance, until the current decade, laparoscopic pancreatic surgery had not been performed for its complicated anatomy. But laparoscopic distal pancreatectomy (LDP) has been widely accepted as a standard treatment for body and tail pancreatic cancer because there is no anastomosis in it, and LDP has gradually become the first choice for these cancers in clinical work. Although there are several studies about the comparison between LDP and ODP, most are retrospective and there is no agreement in surgical margin, lymph node numbers and prognosis to identify the oncological differences between the two surgical approaches. The investigators' pilot study showed that patients with body and tail pancreatic cancer underwent LDP had a better prognosis compared with the ones undergoing ODP, with no statistics differences in postoperative complications and mortality. This perspective RCT study is performed to confirm whether LDP would improve the prognosis for patients with body and tail pancreatic cancer compared with ODP.

NCT ID: NCT03763903 Completed - Laparoscopy Clinical Trials

Comparison of the Effectiveness of 2D Versus 3D Basic Laparoscopic Skills Training

Start date: November 13, 2018
Phase: N/A
Study type: Interventional

The aim of this study is to find out whether basic laparoscopic skills training (FLS tasks) on a standard pelvic trainer using conventional 2D visualization is at least equally effective in terms of skills improvement compared to practicing with 3D visualization. Furthermore, the progress in basic laparoscopic skills improvement for each visualization modality will be analyzed.

NCT ID: NCT03755219 Completed - Recurrence Clinical Trials

Mesh and Mesh Fixation in Laparoscopic Groin Hernia Surgery

Start date: January 1, 2005
Phase:
Study type: Observational [Patient Registry]

The study attempts to quantify the relative risks for recurrence depending on complex combinations of plausible risk factors, in particular mesh, mesh fixation, hernia size and hernia type. For this purpose the investigators will analyze data from the Swedish Hernia Registry (SHR).

NCT ID: NCT03739944 Recruiting - Quality of Life Clinical Trials

Different Surgical Approaches in Patients of Early-stage Cervical Cancer

Start date: November 23, 2018
Phase: Phase 3
Study type: Interventional

This multi-center, randomized controlled study aims to compare the survival outcomes (including overall survival, progression-free survival and disease-free survival between Chinese uterine cervical patients receiving different surgical routes (laparotomy and laparoscopy) for radical hysterectomy or trachelectomy, which is the primary study objective. All patients with uterine cervical cancer of FIGO stage IA1 (with lymphovascular space invasion), IA2 and IB1 will be included and randomized into two groups: laparotomy and laparoscopy groups for radical hysterectomy or trachelectomy. Secondary study objectives include: patterns of recurrence, treatment-associated morbidity (6 months from surgery), cost-effectiveness, pelvic floor function, and quality of life.

NCT ID: NCT03738969 Recruiting - Recurrence Clinical Trials

Longitudinal Study of Different Surgical Approaches in Chinese Patients of Uterine Cervical Cancer

Start date: November 10, 2018
Phase:
Study type: Observational

This multi-center longitudinal study aims to compare the survival outcomes (including overall survival, progression-free survival and disease-free survival between uterine cervical patients receiving different surgical routes (vaginal, laparotomy and laparoscopy), which is the primary study objective. All clinical and pathological data would be retracted from case reviews, and all survival data would be reached by clinic, telephone and mail follow-up. This study also would analyze the impact on survival outcomes of other factors, including nerve-sparing techniques, neoadjuvant chemotherapy, neoadjuvant radiotherapy and infection of human papillomavirus. The predictive effects of different following protocol and imaging plans will be also compared. Last, the influences of surgical routes on the fertility outcomes (pregnancy and its complications) and the ovarian reserve are important secondary study objectives.

NCT ID: NCT03698604 Completed - Laparoscopy Clinical Trials

Total Laparoscopic Hysterectomy Versus Total Abdominal Hysterectomy in Women With Endometrial Neoplasia

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

The aim of this study is to compare operative time between total laparoscopy hysterectomy with bilateral salpingoophrectomy (TLH+BSO) versus total abdominal hysterectomy and bilateral salpingooophorectomy (TAH+BSO) in women with uterine neoplasia.

NCT ID: NCT03684291 Recruiting - Laparoscopy Clinical Trials

Hemodynamic Effects of Ventilation Modes

Start date: October 1, 2018
Phase:
Study type: Observational

Different ventilation modes can be used in laparoscopic surgeries. These surgeries are performed in steep Trendelenburg position with serious hemodynamic disturbances. This study aims to observe the hemodynamic effects of two different ventilation modes in laparoscopic gynecologic surgery performed in steep Trendelenburg position.

NCT ID: NCT03652506 Not yet recruiting - Laparoscopy Clinical Trials

The Impact of Anterior Abdominal Wall Tissue Oxygenation During Pneumoperitoneum of Regional Anesthesia Methods

Start date: August 28, 2018
Phase: N/A
Study type: Interventional

During laparoscopic surgery, the abdomen is inflated with carbon dioxide for abdominal imaging and increased intraabdominal pressure affects intraabdominal structures and abdominal wall.

NCT ID: NCT03640741 Completed - Laparoscopy Clinical Trials

Changes in Cerebral Oxygenation Studies During Laparoscopy Procedure

Start date: July 11, 2016
Phase:
Study type: Observational

The motivation results from the fact, that an intra-abdominal pressure is correlated with cerebral perfusion, in a mechanism of reducing venous outflow. Moreover, elevated intra-abdominal pressure leads to increase in intracranial pressure and decrease of cerebral perfusion pressure. The main aim of the study was to investigate an influence of increase in intra-abdominal pressure on cerebral oxygenation measured with the use of non-invasive optical technique.