Clinical Trials Logo
  1. Home
  2. Lactose Intolerance
  3. NCT00395954
  4. Details
NCT00395954 Clinical Trial

Amount of Lactose Causing Symptoms in Lactose Intolerant People

Lactose Intolerance Clinical Trial

Official title:
A Study to Determine the Threshold of Lactose Ingestion That Provokes Symptoms in Lactose Intolerant People.

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00395954
Other study ID # UHL 10217
Secondary ID
Status Completed
Phase Phase 0
First received November 2, 2006
Last updated February 13, 2009
Start date November 2006
Est. completion date June 2007

Study information
Verified date February 2009
Source University Hospitals, Leicester
Contact n/a
Is FDA regulated No
Health authority United Kingdom: Research Ethics Committee
Study type Observational

Clinical Trial Summary

The hypothesis underlying this study is that failure to recognise the role of lactose intolerance among patients has led to inappropriate dietary advice and treatment with drugs that contain lactose as a filler. These failures exacerbate symptoms and lead to the unnecessary use of immune suppressant drugs.

This study will identify the threshold at which symptoms of lactose intolerance develop, to provide appropriate advice and treatment in the management of patients.

Recruitment information / eligibility
Status Completed
Enrollment 48
Est. completion date June 2007
Est. primary completion date June 2007
Accepts healthy volunteers No
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

- Confirmed lactose intolerance demonstrated with a lactose intolerance test.

- Adherence to a lactose free diet for at least four days before the start of the study.

Exclusion Criteria:

- Failure to adhere to a lactose free diet.

- People who are on lactose containing medications.

- Pregnancy.

- Unwillingness to comply with study outline.

Study Design

Time Perspective: Prospective

Related Conditions & MeSH terms

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
University Hospitals, Leicester
See also
  Status Clinical Trial Phase
Not yet recruiting NCT05100719 - The Role of Irritable Bowel Syndrome in Lactose Intolerance (LION) N/A
Completed NCT02518295 - β-galactosidase Producing Probiotic Strains to Improve Lactose Digestion N/A
Completed NCT00599859 - Effects of Lactose on Fecal Microflora N/A
Completed NCT02636413 - Evaluation of LacTEST for the Diagnosis of Hypolactasia in Adults and Elderly Patients Presenting With Clinical Symptoms of Lactose Intolerance Phase 4
Completed NCT02406469 - Effects Comparison of A1 and A2 Milk on Gastrointestinal Physiology, Symptoms and Cognitive Behavior Phase 4
Terminated NCT00247806 - Prevalence of Lactose Intolerance Following Stem Cell Transplantation Phase 1
Completed NCT03814668 - Effect of Probiotic Supplementation on Lactose Maldigestion Induced by Lactose Solution N/A
Completed NCT03860051 - Association Between Lactase Deficiency, and the Small Intestinal Microbiome in Adults.
Not yet recruiting NCT06107088 - Effect of a Combination of Lactase and L. Salivarius DSM 34078 in Individuals With Lactose Intolerance N/A
Completed NCT02703987 - HYBRID: Hydrogen Breath Test in Lactose Digestion N/A
Completed NCT01593800 - The Effect of Probiotics on Lactose Intolerance N/A
Completed NCT04164394 - Effect of I31 Probiotic on Lactose Intolerance N/A
Recruiting NCT05668468 - A Bifido Bacteria to Improve Lactose Digestion and Tolerance N/A
Completed NCT03563846 - Effect of a Standard Meal on the Pharmacokinetic Profile of RP-G28 in Healthy Adult Male and Female Subjects Phase 1
Recruiting NCT02085889 - Fructose and Lactose Intolerance and Malabsorption in Functional Gastrointestinal Disorders
Completed NCT03597516 - Evaluation of the Efficacy, Durability, Safety, and Tolerability of RP-G28 in Patients With Lactose Intolerance Phase 3
Not yet recruiting NCT03563859 - Evaluation of Efficacy, Durability, Safety, and Tolerability of RP-G28 in Patients With Lactose Intolerance Phase 3
Completed NCT02171403 - Comparison of the Colonic Metabolism in Patients With Lactose Intolerance and Healthy Controls N/A
Completed NCT01145586 - A Non-inferiority, Multicenter and Randomized, Multiple-Dose Study About a Treatment to Hypolactasia Phase 3
Completed NCT02902016 - Modulation of Lactase Expression by a New PPARgamma Ligand in Duodenal Biopsies N/A