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Modulation of Lactase Expression by a New PPARgamma Ligand in Duodenal Biopsies

Lactose Intolerance Clinical Trial

Official title:
Modulation of Lactase Expression by a New Synthetic PPARgamma Ligand in Ex-vivo Cultures of Duodenal Biopsies

Clinical Trial Summary

This study is designed to assess the effect of a new PPARgamma modulator on the expression and activity of the lactase enzyme in human intestinal epithelial cells. Based on their previous experimental results, the investigators hypothesized that modulating intestinal PPARgamma activity is a new pharmacological mechanism allowing the control of lactase expression and activity in the gut

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02902016
Study type Interventional
Source University Hospital, Lille
Contact
Status Completed
Phase N/A
Start date July 16, 2015
Completion date September 2017
View Details
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