Lactation Clinical Trial
Official title:
The Placental and Mammary Transfer of Lutein and Zeaxanthin Into the Fetus and the Breast-fed Infant
The clinical trial aspect of this study is the provision of a lutein supplement to lactating women and compare the amount of lutein in the milk and blood with lactating women who do not receive the lutein supplement.
About one-fourth of preterm infants who weight less than 2 3/4 pounds at birth develop an eye problem. This problem occurs in the retina (back of the eye) and may result in blindness. This eye problem is called the retinopathy of prematurity(ROP). There are two yellow pigments in the retina called lutein and zeaxanthin. These pigments may protect the retina from being damaged by light. They may also protect the retina from being damaged by oxygen. These pigments are transferred from the mother to the baby. Most of this takes place during the last trimester of pregnancy. The situation could be worse if the baby receives formula. Most baby formulas do not contain lutein and zeaxanthin; breast milk does. Another worry is that breast milk may not have enough lutein and zeaxanthin if the mother does not eat enough vegetables and fruits. The purpose of this study is to measure the transfer of lutein and zeaxanthin from the mother to the baby, to measure the amount of lutein and zeaxanthin in breast milk, to find out if taking a lutein supplement will increase the amount of lutein in breast milk and to find out if dietary lutein and zeaxanthin are involved in the development of the retinopathy of prematurity (ROP). ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02542527 -
Evaluation of the Functionality of a Fluid Filled Single Breast Pump
|
N/A | |
| Terminated |
NCT02755194 -
"Drugs in Lactation" Analysis Consortium
|
||
| Terminated |
NCT00851591 -
Effect of Fenugreek on Milk Production
|
N/A | |
| Withdrawn |
NCT00181649 -
Recombinant Human Prolactin for Lactation Induction
|
Phase 2 | |
| Completed |
NCT00181610 -
Recombinant Human Prolactin for Lactation Induction
|
Phase 2 | |
| Completed |
NCT04024865 -
Domperidone and Risk of Serious Cardiac Events in Postpartum Women
|
||
| Terminated |
NCT02378233 -
Iodine Status in Swedish Lactating Women - Effect of Iodine Supplementation in the Thyroid Function of Mother and Infant
|
N/A | |
| Recruiting |
NCT06203444 -
An Open-label Study to Evaluate the Pharmacokinetics of Oral Tenapanor in Breast Milk of Lactating Females
|
Phase 1 | |
| Completed |
NCT01747668 -
Lactation Fortification Study
|
Phase 3 | |
| Completed |
NCT02621827 -
Vitamin D Half-life in Pregnancy and Lactation
|
N/A | |
| Completed |
NCT01463202 -
Timing of Postpartum Depot Medroxyprogesterone Acetate Administration on Breastfeeding, Contraceptive Continuation, and Depression
|
Phase 4 | |
| Terminated |
NCT04146909 -
The Effect of Lactation on Insulin Sensitivity and Lipolysis in Women
|
N/A | |
| Completed |
NCT04593719 -
Effect of Lactation Management Model on Breastfeeding Process
|
N/A | |
| Completed |
NCT01548313 -
The Role of Human Milk in Development of Breast Fed Child's Intestinal Microbiota
|
||
| Completed |
NCT02690675 -
Iron Supplement Effect on Child Development
|
N/A | |
| Completed |
NCT05123183 -
Nonpharmacological Methods and Lactation
|
N/A | |
| Completed |
NCT03091985 -
Influence of the Brownie Breast Shield on the Dynamics of Milk Removal
|
N/A | |
| Completed |
NCT02190448 -
Randomized, Placebo-Controlled Study of an Herbal Tea to Support Lactation
|
N/A | |
| Not yet recruiting |
NCT06264349 -
Women and Maternity: Development of a Nutritional Education Project
|
N/A | |
| Recruiting |
NCT02384655 -
Effect of Fenugreek Use in Mothers of Preterm on Breast Milk Production and Macronutrient Content
|
Phase 1/Phase 2 |