Nutrition Intervention to Address Anemia Among Adolescent Girls in Liberia

Knowledge, Attitudes, Practice Clinical Trial

Official title:

A Study on the Effectiveness of IFA Supplementation, Deworming, and Nutrition Education in Addressing Anemia Among Adolescent Girls in Two Counties in Liberia

Clinical Trial Details — Status: Withdrawn

Administrative data

• NCT number: NCT05073562
• Other study ID #: P00036604
• Status: Withdrawn
• Phase: N/A
• Start date: October 2021
• Est. completion date: December 2021

Study information

• Verified date: November 2021
• Source: Boston Children's Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to evaluate the feasibility and effectiveness of weekly iron and folic acid (IFA) supplementation and one-time deworming treatment at the community level in improving hemoglobin levels among adolescent girls in Liberia, West Africa, and to assess the feasibility and effectiveness of a targeted nutrition education program in improving nutrition knowledge, attitudes, and practices in the same population.

Recruitment information / eligibility

• Status: Withdrawn
• Enrollment: 0
• Est. completion date: December 2021
• Est. primary completion date: December 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 10 Years to 19 Years

Eligibility

Inclusion Criteria:

• Adolescent girl aged 10 - 19 years at the time of enrollment

• Lives within the selected study communities in Montserrado or Margibi counties

• Caregiver/adolescent consents to participate in the study

Exclusion Criteria:

• Currently pregnant

• Active malaria infection as defined by positive rapid diagnostic test (RDT)

• Severe acute malnutrition at the time of enrollment

• Known malignancy

• Known sickle cell disease

Related Conditions & MeSH terms

• Adolescent Development
• Anemia
• Anemia, Iron-Deficiency
• Deficiency Diseases
• Folic Acid Deficiency
• Folic Acid Deficiency Anemia, Dietary
• Food Habits
• Iron Deficiency Anemia Treatment
• Knowledge, Attitudes, Practice
• Malnutrition
• Nutritional Anemia
• Nutritional Deficiency

Intervention

Dietary Supplement:
• Iron and folic acid (IFA) supplementation
Weekly IFA supplementation for duration of the study.

Behavioral:
• Targeted nutrition education
Structured nutrition education package delivered at household level by trained Community Health Assistants (CHAs)

Drug:
• Mebendazole Pill
One-time deworming treatment with mebendazole.

Other:
• Standard nutrition services
Basic nutrition services currently provided at the health facility and at community level in Liberia

Locations

Country	Name	City	State
n/a

Sponsors (4)

Lead Sponsor	Collaborator
Boston Children's Hospital	Liberia Institute of Statistics and Geo-Information Services, Ministry of Health, Liberia, UNICEF

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in participants' hemoglobin level from enrollment to completion of the study	Point of care hemoglobin testing will be conducted at enrollment and at the conclusion of the study.	Baseline and Week 12
Secondary	Changes in responses to questions in the Nutrition Knowledge, Attitudes, and Practice (KAP) survey from baseline to follow up evaluation	Increase in nutrition-related knowledge, and improvements in nutrition practices as evidenced by changes in responses to the KAP survey, which is based on validated measures of nutrition-related knowledge, attitudes, and practices, and has been modified for appropriateness to the target population of this study.	Baseline and Week 12
Secondary	Feasibility of targeted intervention for scale-up to country-wide enhanced nutrition services	Successful completion of study visits by Community Health Assistants, specifically ability to conduct every scheduled visit without skipping visits or households, within the timeframe of scheduled work day.	12 weeks