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Knee Replacement Surgery clinical trials

View clinical trials related to Knee Replacement Surgery.

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NCT ID: NCT06382285 Not yet recruiting - Clinical trials for Knee Replacement Surgery

The Effect of a Prolonged Peripheral Nerve Block on the Level of Pain After a Knee Replacement

Start date: October 30, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to examine the effect of a prolonged peripheral nerve block (utilizing continuous adductor canal block) on the level of pain after a knee replacement surgery

NCT ID: NCT05246007 Not yet recruiting - Dexmedetomidine Clinical Trials

Nocturnal Low-dose Dexmedetomidine Infusion and Perioperative Sleep Quality

Start date: May 2022
Phase: N/A
Study type: Interventional

Sleep disturbances are prevalent in older patients with osteoarthrosis or fracture scheduled for knee or hip replacement surgery. The occurrence of sleep disturbances is associated with worse outcomes including increased risk of delirium and cardiac events, and worsened functional recovery. Dexmedetomidine is a highly selective α2-adrenergic agonist with sedative, anxiolytic, and analgesic properties. It exerts sedative effects via activating the endogenous sleep pathways and produces a state like non-rapid eye movement sleep, which is different from opioid- and benzodiazepine-induced sedation. Night-time infusion of low-dose dexmedetomidine may improve sleep quality. However, evidence in this aspect is limited.