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Knee Replacement clinical trials

View clinical trials related to Knee Replacement.

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NCT ID: NCT06064318 Completed - Knee Replacement Clinical Trials

Prevalence and Incidence of Multiple Revisions Following Knee Arthroplasty in Denmark 1998-2021: A Nationwide Population-based Study

EMKAR ONE
Start date: February 1, 2023
Phase:
Study type: Observational

The purpose of this study is to investigate the incidence and prevalence rates of multiply revised knee arthroplasty patients in Denmark from 1998-2021.

NCT ID: NCT05635916 Completed - Clinical trials for Total Knee Arthroplasty

Trial of Liposomal Bupivacaine for TKA

Start date: September 22, 2022
Phase: Phase 4
Study type: Interventional

Total knee arthroplasty (TKA), also known as a knee replacement, is a procedure performed to reduce severe pain and improve function of the joint. Managing postoperative pain can be challenging following TKA, and inadequate relief can lead to impaired mobility and persistent opioid use. Adductor canal nerve blocks (ACB), have shown significant benefit in improving postoperative analgesia and patient satisfaction. However, the local anesthetic used currently for these blocks only provides temporary relief that wears off within 24 hours. Liposomal bupivacaine is an extended-release local anesthetic agent that can provide up to 72 hours of pain relief, however it is unclear if its use is also effective in ACBs for knee surgery. The purpose of this study is to determine if liposomal bupivacaine is better than conventional bupivacaine in improving pain control, opioid consumption, and length of stay in patients scheduled for TKA.

NCT ID: NCT05459948 Recruiting - Knee Replacement Clinical Trials

The Medacta GMK SpheriKA Post-Marketing Surveillance Study

Start date: July 30, 2022
Phase:
Study type: Observational

This is a Post-Marketing Surveillance of GMK SpheriKA knee stem prosthesis.

NCT ID: NCT05184725 Completed - Prostate Cancer Clinical Trials

CARINAE for Stress Relief in Perioperative Care

CARINAE
Start date: January 10, 2022
Phase: N/A
Study type: Interventional

Preventing pre-surgical stress can help patients achieve positive outcomes on health and well-being. However, very few patients receive adequate stress relief support prior to a surgical procedure. Provision of education and information about the surgery can be a crucial component of the preoperative experience and is inversely related to levels of preoperative anxiety. However, resource constraints make face-to-face education sessions untenable, given cost considerations and time investment by trained health personnel. Interventions based on mobile health (mHealth) technologies, geared towards increasing familiarity with surgical procedures and hospital environments have been shown to help patients feel informed about possible benefits and risks of available treatment options. mHealth apps and Virtual Reality (VR) can offer patients experience in the perioperative environment that can be helpful in empowering patients and enhancing a more positive experience, while reducing stress. However, available applications focus only on providing informative content, neglecting the importance of patient empowerment with a more robust educational curriculum. According to this, the Software as a Medical Device (SaMD) CARINAE, aims to support patients and caregivers during the whole perioperative process. SaMD CARINAE consists of an mHealth mobile application for patients and caregivers, a Virtual Reality headset for patients, and a web application for healthcare professionals.

NCT ID: NCT04328701 Active, not recruiting - Clinical trials for Osteoarthritis, Knee

Prediction of Outcomes Following Total Knee Replacement- Pilot

POKR-p
Start date: April 1, 2018
Phase: N/A
Study type: Interventional

This study seeks to examine multiple risk factors as predictors of pain and function following total knee arthroplasty (TKA). Risk factors will be measured pre-surgically using psychophysical testing procedures, multimodal evaluation of sleep, standardized questionnaires. Additionally, this study will collect pilot data on a brief mindfulness-based cognitive-behavioral treatment that may help to improve long-term TKA outcomes. The pilot study compared TKA patients that received brief mindfulness-based cognitive behavioral therapy (MBCBT) to the treatment-as-usual (TAU) group from the parent study.

NCT ID: NCT04314505 Recruiting - Postoperative Pain Clinical Trials

Opioid-Sparing Protocol Comparing With Opioid-based Protocol After Bilateral Total Knee Arthroplasty

Start date: March 20, 2020
Phase: Phase 4
Study type: Interventional

The concern for the opioid use in the total knee arthroplasty continues to rise in recent decades. Historically, the total knee arthroplasty consumed high doses opioids in the postoperative periods. Compared to the Opioid-Based patient controlled analgesia(PCA), the opioid-sparing protocol may have benefits to decrease the concerns of the opioid use and opioid-related complication and provides the equivalent efficacy for pain control. The purpose of this trial in to provide a novel opioid-sparing protocol (OSP) to evaluate the efficacy for pain control and reducing the immediate postoperative opioid consumption.

NCT ID: NCT04199377 Recruiting - HIP REPLACEMENT Clinical Trials

Retrospective Evaluation of Clinical and Functional Results and Survivorship of Total Knee Replacement and Total Hip Replacement, Both Isolated or Combined.

ALLCCP
Start date: October 20, 2017
Phase: N/A
Study type: Interventional

Retrospective evaluation of clinical and functional results and survivorship of total knee replacement and total hip replacement, both isolated or combined.

NCT ID: NCT04198389 Active, not recruiting - KNEE REPLACEMENT Clinical Trials

Retrospective Clinical and Functional Evaluation of Patients Undergoing Knee Replacement With Small Implants

SMALLIMPL
Start date: July 20, 2017
Phase: N/A
Study type: Interventional

Retrospective evaluation of: Functional results Clinical results Survivorship of knee replacement performed with small implants, isolated or combined

NCT ID: NCT04167787 Recruiting - Knee Replacement Clinical Trials

Intelligent Operating Room (InOR) for Orthopaedic Surgery

InOR
Start date: October 10, 2019
Phase:
Study type: Observational

The objective of the study is to evaluate the usefulness of digital technologies to support surgical teams before, during, and after an operation.

NCT ID: NCT04099355 Withdrawn - Arthropathy of Knee Clinical Trials

Investigating the Effect of Dronabinol on Post-surgical Pain

Start date: September 1, 2025
Phase: Early Phase 1
Study type: Interventional

This study is designed to investigate the effect of dronabinol on post operative pain in patients undergoing total knee replacement (for their own clinical care).